NDLI: Structure of miniature swine class II DRB genes: conservation of hypervariable amino acid residues between distantly related mammalian species.

Please wait, while we are loading the content...

Year: 2017 Volume: 114

Year: 2016 Volume: 113

Year: 2015 Volume: 112

Year: 2014 Volume: 111

Year: 2013 Volume: 110

Year: 2012 Volume: 109

Year: 2011 Volume: 108

Year: 2010 Volume: 107

Year: 2009 Volume: 106

Year: 2008 Volume: 105

Year: 2007 Volume: 104

Year: 2006 Volume: 103

Year: 2005 Volume: 102

Year: 2004 Volume: 101

Year: 2003 Volume: 100

Year: 2002 Volume: 99

Year: 2001 Volume: 98

Year: 2000 Volume: 97

Year: 1999 Volume: 96

Year: 1998 Volume: 95

Year: 1997 Volume: 94

Year: 1996 Volume: 93

Year: 1995 Volume: 92

Year: 1994 Volume: 91

Year: 1993 Volume: 90

Year: 1992 Volume: 89

Year: 1991 Volume: 88

Year: 1990 Volume: 87

Year: 1990 Volume: 87 Issue: 24

Excision in algebraic K-theory and Karoubi's conjecture.

Prehistoric extinction of birds on Mangaia, Cook Islands, Polynesia.

Invasion resistance arises in strongly interacting species-rich model competition communities.

A general bijective algorithm for trees.

Variation in repeated nucleotide sequences sheds light on the phylogeny of the wheat B and G genomes.

Effects of auxin and abscisic acid on cytosolic calcium and pH in plant cells.

When can ants discriminate the sex of brood? A new aspect of queen-worker conflict.

Simultaneous monitoring of light-induced changes in protein side-group protonation, chromophore isomerization, and backbone motion of bacteriorhodopsin by time-resolved Fourier-transform infrared spectroscopy.

Genetic and morphological analysis of a maize-teosinte F2 population: implications for the origin of maize.

A 75-kDa polypeptide, located primarily at the plasma membrane of carrot cell-suspension cultures, is photoaffinity labeled by the calcium channel blocker LU 49888.

Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells.

Structure and expression of cytosolic cyclophilin/peptidyl-prolyl cis-trans isomerase of higher plants and production of active tomato cyclophilin in Escherichia coli.

Anti-Fas monoclonal antibody is cytocidal to human immunodeficiency virus-infected cells without augmenting viral replication.

Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.

Neuropathological changes in transgenic mice carrying copies of a transcriptionally activated Mos protooncogene.

Molecular epitope identification by limited proteolysis of an immobilized antigen-antibody complex and mass spectrometric peptide mapping.

Adenovirus 12S E1A gene represses differentiation of F9 teratocarcinoma cells.

Characterization of a splicing mutation in group A xeroderma pigmentosum.

Expression of neurophysin-related precursor in cell membranes of a small-cell lung carcinoma.

The role of an autoantigen, histidyl-tRNA synthetase, in the induction and maintenance of autoimmunity.

Evolution of sequences encoding the principal neutralization epitope of human immunodeficiency virus 1 is host dependent, rapid, and continuous.

Cloning and expression of N-acetylglucosaminyltransferase I, the medial Golgi transferase that initiates complex N-linked carbohydrate formation.

Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site.

Polyamines potentiate responses of N-methyl-D-aspartate receptors expressed in xenopus oocytes.

Transgene-induced mutation of the murine steel locus.

In vitro effect of delta 9-tetrahydrocannabinol to stimulate somatostatin release and block that of luteinizing hormone-releasing hormone by suppression of the release of prostaglandin E2.

Cross-linked A alpha.gamma chain hybrids serve as unique markers for fibrinogen polymerized by tissue transglutaminase.

Susceptibility or resistance to lysis by alloreactive natural killer cells is governed by a gene in the human major histocompatibility complex between BF and HLA-B.

beta-Galactosidase containing a human immunodeficiency virus protease cleavage site is cleaved and inactivated by human immunodeficiency virus protease.

Mutational analysis of an archaebacterial promoter: essential role of a TATA box for transcription efficiency and start-site selection in vitro.

A bacterial peptide acting as a plant nuclear targeting signal: the amino-terminal portion of Agrobacterium VirD2 protein directs a beta-galactosidase fusion protein into tobacco nuclei.

Evolution of Drosophila mitochondrial DNA and the history of the melanogaster subgroup.

Mutants of Saccharomyces cerevisiae defective in the farnesylation of Ras proteins.

Genetic basis of the difference in alcohol dehydrogenase expression between Drosophila melanogaster and Drosophila simulans.

Processing of the mother-cell sigma factor, sigma K, may depend on events occurring in the forespore during Bacillus subtilis development.

Development of a stable Leishmania expression vector and application to the study of parasite surface antigen genes.

Structure and differential expression of two genes encoding carbonic anhydrase in Chlamydomonas reinhardtii.

Structure of miniature swine class II DRB genes: conservation of hypervariable amino acid residues between distantly related mammalian species.

Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42.

Site-specific cleavage of duplex DNA by a semisynthetic nuclease via triple-helix formation.

Brain magnetic resonance imaging with contrast dependent on blood oxygenation.

Expression of ToxR, the transcriptional activator of the virulence factors in Vibrio cholerae, is modulated by the heat shock response.

Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster.

Preparation and crystallization of a human immunodeficiency virus p24-Fab complex.

Coordinate occupancy of AP-1 sites in the vitamin D-responsive and CCAAT box elements by Fos-Jun in the osteocalcin gene: model for phenotype suppression of transcription.

Delayed start-up of kinesin-driven microtubule gliding following inhibition by adenosine 5'-[beta,gamma-imido]triphosphate.

Ligand-dependent structural variations in Escherichia coli F1 ATPase revealed by cryoelectron microscopy.

Characterization of the steroid-metabolizing capacity of the hepatic cytochrome P450IIC5 expressed in COS-1 cells: 3 beta-hydroxysteroid dehydrogenase/delta 5----4 isomerase type activity.

Method for identifying microbial antigens that stimulate specific lymphocyte responses: application to Salmonella.

Cation-dependent mannose 6-phosphate receptor contains two internalization signals in its cytoplasmic domain.

Loss of DNA-membrane interactions and cessation of DNA synthesis in myeloperoxidase-treated Escherichia coli.

Expression cloning of a cDNA encoding the mouse pituitary thyrotropin-releasing hormone receptor.

Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.

Eukaryotic initiation factor 3 is required for poliovirus 2A protease-induced cleavage of the p220 component of eukaryotic initiation factor 4F.

Isolation and heterologous expression of a cDNA encoding bovine inositol polyphosphate 1-phosphatase.

In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment.

Identification of mitosis-specific p65 dimer as a component of human M phase-promoting factor.

A long terminal repeat-containing retrotransposon is mobilized during hybrid dysgenesis in Drosophila virilis.

Autoimmune preganglionic sympathectomy induced by acetylcholinesterase antibodies.

Calcium currents recorded from a vertebrate presynaptic nerve terminal are resistant to the dihydropyridine nifedipine.

Steroidogenic activity of a peptide specified by the reversed sequence of corticotropin mRNA.

Studies on the initiation and elongation reactions in the simian virus 40 DNA replication system.

Activation of early events of the mitogenic response by a P2Y purinoceptor with covalently bound 3'-O-(4-benzoyl)-benzoyladenosine 5'-triphosphate.

Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3.

An intrinsic membrane glycoprotein with cytosolically oriented n-linked sugars.

Long-term expression of a T-cell receptor beta-chain gene in mice reconstituted with retrovirus-infected hematopoietic stem cells.

Activation of erythropoietin receptors by Friend viral gp55 and by erythropoietin and down-modulation by the murine Fv-2r resistance gene.

Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression.

Physiological induction and reversal of focus formation and tumorigenicity in NIH 3T3 cells.

Molecular clock of viral evolution, and the neutral theory.

NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells.

Primary combined immunodeficiency resulting from defective transcription of multiple T-cell lymphokine genes.

Cryoglobulinemia induced by a murine IgG3 rheumatoid factor: skin vasculitis and glomerulonephritis arise from distinct pathogenic mechanisms.

Beneficial effects of x-irradiation on recovery of lesioned mammalian central nervous tissue.

Positive transcriptional feedback at the bvg locus controls expression of virulence factors in Bordetella pertussis. (Journal: Proceedings of the National Academy of Sciences of the United States of America Volume: 87 Issue: 24)

The low-affinity Ca2(+)-binding sites in cardiac/slow skeletal muscle troponin C perform distinct functions: site I alone cannot trigger contraction.

Adenovirus early region 4 stimulates mRNA accumulation via 5' introns.

Cell line-specific differences in the control of cell cycle progression in the absence of mitosis.

Molecular mechanisms in down-regulation of tumor necrosis factor expression.

High-resolution structure of a mutagenic lesion in DNA.

Analysis of interleukin 2 and various effector cell populations in adoptive immunotherapy of 9L rat gliosarcoma: allogeneic cytotoxic T lymphocytes prevent tumor take.

A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo.

Dynamics of the distribution of cyclic AMP-dependent protein kinase in living cells.

Molecular analysis of human argininosuccinate lyase: mutant characterization and alternative splicing of the coding region.

Transcriptional regulation of interleukin 3 gene expression in T lymphocytes.

Stability and activity of human immunodeficiency virus protease: comparison of the natural dimer with a homologous, single-chain tethered dimer.

Molecular cloning and construction of the coding region for human acetylcholinesterase reveals a G + C-rich attenuating structure.

Dopamine induces neurite retraction in retinal horizontal cells via diacylglycerol and protein kinase C.

Involvement of transforming growth factor alpha in the release of luteinizing hormone-releasing hormone from the developing female hypothalamus.

Expression of the thymus leukemia antigen in mouse intestinal epithelium.

Polymorphism at the self-incompatibility locus in Solanaceae predates speciation.

Phospholipase A2 activity of low density lipoprotein: evidence for an intrinsic phospholipase A2 activity of apoprotein B-100.

A different cytochrome P450 form is induced in primary cultures of rat hepatocytes.

In vitro regulation of a SIN3-dependent DNA-binding activity by stimulatory and inhibitory factors.

Isolation and amino acid sequences of squirrel monkey (Saimiri sciurea) insulin and glucagon.

Human tumor necrosis factor alpha gene regulation by virus and lipopolysaccharide.

Cell mutants defective in synthesizing a heparan sulfate proteoglycan with regions of defined monosaccharide sequence.

Boron neutron capture therapy of intracerebral rat gliosarcomas.

Cloning of cDNAs encoding amphibian bombesin: evidence for the relationship between bombesin and gastrin-releasing peptide.

A myo-inositol pool utilized for phosphatidylinositol synthesis is depleted in sciatic nerve from rats with streptozotocin-induced diabetes.

Structural alterations of nerve during cuff compression.

Specificity of cell-cell coupling in rat optic nerve astrocytes in vitro.

Molecular cloning, functional expression, and chromosomal localization of mouse hepatocyte nuclear factor 1.

Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone.

Cytochrome a1 of acetobacter aceti is a cytochrome ba functioning as ubiquinol oxidase.

Uv-visible spectroscopy of bacteriorhodopsin mutants: substitution of Arg-82, Asp-85, Tyr-185, and Asp-212 results in abnormal light-dark adaptation.

Repair of O6-ethylguanine in DNA protects rat 208F cells from tumorigenic conversion by N-ethyl-N-nitrosourea.

Glucose-induced translocation of protein kinase C in rat pancreatic islets.

Characterization of iron superoxide dismutase cDNAs from plants obtained by genetic complementation in Escherichia coli.

Meiotic recombination between yeast artificial chromosomes yields a single clone containing the entire BCL2 protooncogene.

Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection.

Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus.

Evidence that down-regulation of beta-cell glucose transporters in non-insulin-dependent diabetes may be the cause of diabetic hyperglycemia.

Frequent mutation of the p53 gene in human esophageal cancer.

Cytogenetic damage induced by folate deficiency in mice is enhanced by caffeine.

Conserved enzymes mediate the early reactions of carotenoid biosynthesis in nonphotosynthetic and photosynthetic prokaryotes.

Year: 1990 Volume: 87 Issue: 23

Year: 1990 Volume: 87 Issue: 22

Year: 1990 Volume: 87 Issue: 21

Year: 1990 Volume: 87 Issue: 20

Year: 1990 Volume: 87 Issue: 19

Year: 1990 Volume: 87 Issue: 18

Year: 1990 Volume: 87 Issue: 17

Year: 1990 Volume: 87 Issue: 16

Year: 1990 Volume: 87 Issue: 15

Year: 1990 Volume: 87 Issue: 14

Year: 1990 Volume: 87 Issue: 13

Year: 1990 Volume: 87 Issue: 12

Year: 1990 Volume: 87 Issue: 11

Year: 1990 Volume: 87 Issue: 10

Year: 1990 Volume: 87 Issue: 9

Year: 1990 Volume: 87 Issue: 8

Year: 1990 Volume: 87 Issue: 7

Year: 1990 Volume: 87 Issue: 6

Year: 1990 Volume: 87 Issue: 5

Year: 1990 Volume: 87 Issue: 4

Year: 1990 Volume: 87 Issue: 3

Year: 1990 Volume: 87 Issue: 2

Year: 1990 Volume: 87 Issue: 1

Year: 1990 Volume: 87 Issue: Suppl

Year: 1989 Volume: 86

Year: 1988 Volume: 85

Year: 1987 Volume: 84

Year: 1986 Volume: 83

Year: 1985 Volume: 82

Year: 1984 Volume: 81

Year: 1983 Volume: 80

Year: 1982 Volume: 79

Year: 1981 Volume: 78

Year: 1980 Volume: 77

Year: 1979 Volume: 76

Year: 1978 Volume: 75

Year: 1977 Volume: 74

Year: 1976 Volume: 73

Year: 1975 Volume: 72

Year: 1974 Volume: 71

Year: 1973 Volume: 70

Year: 1972 Volume: 69

Year: 1971 Volume: 68

Year: 1970 Volume: 67

Year: 1970 Volume: 66

Year: 1970 Volume: 65

Year: 1969 Volume: 64

Year: 1969 Volume: 63

Year: 1969 Volume: 62

Year: 1968 Volume: 61

Year: 1968 Volume: 60

Year: 1968 Volume: 59

Year: 1967 Volume: 58

Year: 1967 Volume: 57

Year: 1966 Volume: 56

Year: 1966 Volume: 55

Structure of miniature swine class II DRB genes: conservation of hypervariable amino acid residues between distantly related mammalian species.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Pratt, K. Leguern, C. Gustafsson, K. Hirsch, F. Sachs, D. H. Germana, S.
Description	Author Affiliation: Gustafsson K ( Transplantation Biology Section, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.);
Abstract	As part of our studies of the class II genes of miniature swine, we have isolated and characterized cDNA clones corresponding to DRB genes from two major histocompatibility complex homozygous strains. Comparison of the sequences of these clones to those of human DRB genes revealed a striking amino acid homology between the hypervariable residues of SLA-DRBc and the human DRB1-0101 allele. The percentage of differences in these residues between the pig DRBc allele and the human DRB1-0101 allele was significantly lower (29%) than that between the DRB1-0101 allele and all other human alleles (average, 66.2%). This similarity was not seen in a comparison of the number of silent substitutions, by which the swine DRBc and the human DRB-0101 differed. Since phenotypic selection operates at the level of protein products rather than nucleotide sequences, these data suggest the existence of selective mechanisms that have resulted in similar hypervariable regions in certain alleles even in these widely disparate species. Consistent with this hypothesis, an examination of available murine and bovine class II sequences revealed a homology in hypervariable residues between the human DRB1-1401 allele and the mouse E beta s allele as well as a cow DRB allele. Consideration of these data along with intraspecies allelic sequence comparisons suggests that at least some of the interspecies similarities have emerged as the result of convergent evolution, possibly as the result of a need to react to common pathogens.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	24
Volume Number	87
Language	English
Publisher	National Academy of Sciences
Publisher Date	1990-01-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Genes, MHC Class II HLA-DR Antigens Genetics Swine, Miniature Immunology Amino Acid Sequence Animals Biological Evolution Cloning, Molecular Gene Library Molecular Sequence Data Sequence Homology, Nucleic Acid Spleen Swine Comparative Study Research Support, Non-U.S. Gov't Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in