NDLI: Evolution of the major histocompatibility complex: molecular cloning of major histocompatibility complex class I from the amphibian Xenopus.

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Evolution of the major histocompatibility complex: molecular cloning of major histocompatibility complex class I from the amphibian Xenopus.

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Two-dimensional life?

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Evolution of the major histocompatibility complex: molecular cloning of major histocompatibility complex class I from the amphibian Xenopus.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Kasahara, M. Flajnik, M. F. Kramer, J. Canel, C.
Description	Author Affiliation: Flajnik MF ( Department of Microbiology and Immunology, University of Miami, FL 33101.);
Abstract	Class I major histocompatibility complex (MHC) cDNA clones have been isolated from an expression library derived from mRNA of an MHC homozygous Xenopus laevis. The nucleotide and predicted amino acid sequences show definite similarity to MHC class I molecules of higher vertebrates. The immunoglobulin-like alpha-3 domain is more similar to the immunoglobulin-like domains of mammalian class II beta chains than to those of mammalian class I molecules, and a tree based on nucleotide sequences of representative MHC genes is presented.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	2
Volume Number	88
Language	English
Publisher	National Academy of Sciences
Publisher Date	1991-02-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Biological Evolution Genes, MHC Class I Major Histocompatibility Complex Xenopus Laevis Immunology Amino Acid Sequence Animals Cloning, Molecular Gene Library Molecular Sequence Data Phylogeny RNA Genetics Isolation & Purification Sequence Homology, Nucleic Acid Comparative Study Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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