NDLI: Theory for normal and impaired experience-dependent plasticity in neocortex of adult rats.

Please wait, while we are loading the content...

Year: 2017 Volume: 114

Year: 2016 Volume: 113

Year: 2015 Volume: 112

Year: 2014 Volume: 111

Year: 2013 Volume: 110

Year: 2012 Volume: 109

Year: 2011 Volume: 108

Year: 2010 Volume: 107

Year: 2009 Volume: 106

Year: 2008 Volume: 105

Year: 2007 Volume: 104

Year: 2006 Volume: 103

Year: 2005 Volume: 102

Year: 2004 Volume: 101

Year: 2003 Volume: 100

Year: 2002 Volume: 99

Year: 2001 Volume: 98

Year: 2001 Volume: 98 Issue: 26

Year: 2001 Volume: 98 Issue: 25

Year: 2001 Volume: 98 Issue: 24

Year: 2001 Volume: 98 Issue: 23

Year: 2001 Volume: 98 Issue: 22

Year: 2001 Volume: 98 Issue: 21

Year: 2001 Volume: 98 Issue: 20

Year: 2001 Volume: 98 Issue: 19

Year: 2001 Volume: 98 Issue: 18

Year: 2001 Volume: 98 Issue: 17

Year: 2001 Volume: 98 Issue: 16

Year: 2001 Volume: 98 Issue: 15

Year: 2001 Volume: 98 Issue: 14

Year: 2001 Volume: 98 Issue: 13

Year: 2001 Volume: 98 Issue: 12

Year: 2001 Volume: 98 Issue: 11

Year: 2001 Volume: 98 Issue: 10

Year: 2001 Volume: 98 Issue: 9

Year: 2001 Volume: 98 Issue: 8

Year: 2001 Volume: 98 Issue: 7

Year: 2001 Volume: 98 Issue: 6

Year: 2001 Volume: 98 Issue: 5

Planetary exploration in the time of astrobiology: protecting against biological contamination.

Use of spacecraft data to derive regions on Mars where liquid water would be stable.

Extraterrestrial amino acids in Orgueil and Ivuna: tracing the parent body of CI type carbonaceous chondrites.

Organic protomolecule assembly in igneous minerals

Oxygen isotope ratios of PO4: an inorganic indicator of enzymatic activity and P metabolism and a new biomarker in the search for life.

Keeping Mars warm with new super greenhouse gases.

A novel microbial habitat in the mid-ocean ridge subseafloor.

Truncated hexa-octahedral magnetite crystals in ALH84001: Presumptive biosignatures

The origin of atmospheric oxygen on Earth: The innovation of oxygenic photosynthesis

Chains of magnetite crystals in the meteorite ALH84001: evidence of biological origin.

Constraints on nebular dynamics and chemistry based on observations of annealed magnesium silicate grains in comets and in disks surrounding Herbig Ae/Be stars.

Solvent effects on the energy landscapes and folding kinetics of polyalanine.

On the acidity and reactivity of HNO in aqueous solution and biological systems.

Delineating developmental and metabolic pathways in vivo by expression profiling using the RIKEN set of 18,816 full-length enriched mouse cDNA arrays.

Active site mutant transgene confers tolerance to human beta-glucuronidase without affecting the phenotype of MPS VII mice.

pRB induces Sp1 activity by relieving inhibition mediated by MDM2.

Nanohedra: using symmetry to design self assembling protein cages, layers, crystals, and filaments.

Mutated plant lectin library useful to identify different cells.

Distinct roles for the N- and C-terminal regions in the cytotoxicity of pierisin-1, a putative ADP-ribosylating toxin from cabbage butterfly, against mammalian cells.

The nitrite reductase from Pseudomonas aeruginosa: Essential role of two active-site histidines in the catalytic and structural properties

A short segment within the cytoplasmic domain of the neural cell adhesion molecule (N-CAM) is essential for N-CAM-induced NF-kappa B activity in astrocytes.

Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis.

Polar residues drive association of polyleucine transmembrane helices.

Identification in mice of two isoforms of the cysteinyl leukotriene 1 receptor that result from alternative splicing.

Arabidopsis cyt1 mutants are deficient in a mannose-1-phosphate guanylyltransferase and point to a requirement of N-linked glycosylation for cellulose biosynthesis.

Twenty-first aminoacyl-tRNA synthetase-suppressor tRNA pairs for possible use in site-specific incorporation of amino acid analogues into proteins in eukaryotes and in eubacteria.

Viral capsid mobility: a dynamic conduit for inactivation.

Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis.

The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals.

Gene elements that affect the longevity of rbcL sequence-containing transcripts in Chlamydomonas reinhardtii chloroplasts.

TRM1, a YY1-like suppressor of rbcS-m3 expression in maize mesophyll cells.

Contributions of distinct quaternary contacts to cooperative operator binding by Mnt repressor.

Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate.

Structural determinants of oxidative folding in proteins.

Zinc metallothionein imported into liver mitochondria modulates respiration.

Fatty acids and hypolipidemic drugs regulate peroxisome proliferator-activated receptors alpha - and gamma-mediated gene expression via liver fatty acid binding protein: a signaling path to the nucleus.

Recent improvements in prediction of protein structure by global optimization of a potential energy function.

Destabilization of Ca2+-free gelsolin may not be responsible for proteolysis in Familial Amyloidosis of Finnish Type.

Capabilities of liposomes for topological transformation.

Dynamics and orientation of N+(CD3)3-bromoacetylcholine bound to its binding site on the nicotinic acetylcholine receptor.

Two different neurodegenerative diseases caused by proteins with similar structures.

Transverse relaxation-optimized NMR spectroscopy with the outer membrane protein OmpX in dihexanoyl phosphatidylcholine micelles.

An unusual pathway of excitation energy deactivation in carotenoids: singlet-to-triplet conversion on an ultrafast timescale in a photosynthetic antenna.

The role of structure, energy landscape, dynamics, and allostery in the enzymatic function of myoglobin

An amyloid-forming peptide from the yeast prion Sup35 reveals a dehydrated beta-sheet structure for amyloid.

Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex

An isolated, surface-expressed I domain of the integrin alphaLbeta2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond.

Locking in alternate conformations of the integrin αLβ2 I domain with disulfide bonds reveals functional relationships among integrin domains

Organellar relationships in the Golgi region of the pancreatic beta cell line, HIT-T15, visualized by high resolution electron tomography.

Kinetics of protein import into isolated Xenopus oocyte nuclei

ARF-GEP(100), a guanine nucleotide-exchange protein for ADP-ribosylation factor 6.

Identification of the endogenous smooth muscle myosin phosphatase-associated kinase

FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle

Analysis of endoplasmic reticulum trafficking signals by combinatorial screening in mammalian cells.

Spatiotemporal dynamics of guanosine 3',5'-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator.

IL-4 inhibits osteoclast formation through a direct action on osteoclast precursors via peroxisome proliferator-activated receptor gamma 1.

Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds.

Identification and dissection of an enhancer controlling epithelial gene expression in skin.

Production of zebrafish germ-line chimeras from embryo cell cultures.

An efficient system for conditional gene expression in embryonic stem cells and in their in vitro and in vivo differentiated derivatives.

Plant growth in elevated $CO_{2}$ alters mitochondrial number and chloroplast fine structure

Effects of elevated atmospheric $CO_{2}$ concentration on leaf dark respiration of Xanthium strumarium in light and in darkness

Paleoclimate and Amerindians: evidence from stable isotopes and atmospheric circulation.

Predator-induced stress makes the pesticide carbaryl more deadly to gray treefrog tadpoles (Hyla versicolor).

Estimation of divergence times from multiprotein sequences for a few mammalian species and several distantly related organisms.

Phylogeny of genes for secretion NTPases: identification of the widespread tadA subfamily and development of a diagnostic key for gene classification.

Positive Darwinian selection drives the evolution of several female reproductive proteins in mammals.

Role of the F-box protein Skp2 in lymphomagenesis

Genomic and genetic dissection of an archaeal regulon.

Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange– Nielsen Syndrome

Somatic mosaicism in Fanconi anemia: evidence of genotypic reversion in lymphohematopoietic stem cells.

Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement.

Establishment of medaka (Oryzias latipes) transgenic lines with the expression of green fluorescent protein fluorescence exclusively in germ cells: a useful model to monitor germ cells in a live vertebrate.

Interaction of a transcriptional repressor with the RNA polymerase II holoenzyme plays a crucial role in repression.

A genomic approach to gene fusion technology.

Defective localization of the NADPH phagocyte oxidase to Salmonella-containing phagosomes in tumor necrosis factor p55 receptor-deficient macrophages.

Impaired survival of T helper cells in the absence of CD4.

Spontaneous retinopathy in HLA-A29 transgenic mice.

Requirement for natural killer T (NKT) cells in the induction of allograft tolerance.

BLNK mediates Syk-dependent Btk activation.

Lack of a role for transforming growth factor-beta in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation.

Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor.

Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells.

Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability.

Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor.

Whole-body and intravital optical imaging of angiogenesis in orthotopically implanted tumors.

NO chemical events in the human airway during the immediate and late antigen-induced asthmatic response.

Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells.

Cardiovascular abnormalities with normal blood pressure in tissue kallikrein-deficient mice.

Top-down morphogenesis of colorectal tumors.

High-sensitivity array analysis of gene expression for the early detection of disseminated breast tumor cells in peripheral blood.

An NO derivative of ursodeoxycholic acid protects against Fas-mediated liver injury by inhibiting caspase activity.

Anti-PSCA mAbs inhibit tumor growth and metastasis formation and prolong the survival of mice bearing human prostate cancer xenografts.

The surface variant antigens of Plasmodium falciparum contain cross-reactive epitopes.

DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans.

Adeno-associated viral vector-mediated gene transfer results in long-term enzymatic and functional correction in multiple organs of Fabry mice.

Antibodies to human fetal erythroid cells from a nonimmune phage antibody library.

Chronic elevation of plasma thioredoxin: inhibition of chemotaxis and curtailment of life expectancy in AIDS.

Alkaline-mediated differential interaction (AMDI): a simple automatable single-nucleotide polymorphism assay.

Mechanisms underlying losses of heterozygosity in human colorectal cancers.

A genetic model provides evidence that the receptor for atrial natriuretic peptide (guanylyl cyclase-A) inhibits cardiac ventricular myocyte hypertrophy.

Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis

Transcriptome of a mouse kidney cortical collecting duct cell line: effects of aldosterone and vasopressin.

Evaluation of the role of heterogeneous nuclear ribonucleoprotein A1 as a host factor in murine coronavirus discontinuous transcription and genome replication.

Subcellular localization of acetyl-CoA carboxylase in the apicomplexan parasite Toxoplasma gondii.

Expression of the Anabaena hetR gene from a copper-regulated promoter leads to heterocyst differentiation under repressing conditions.

Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing.

Comparative genomics of the restriction-modification systems in Helicobacter pylori.

Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes

QscR, a modulator of quorum-sensing signal synthesis and virulence in Pseudomonas aeruginosa.

Effect of rabies virus infection on gene expression in mouse brain.

Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain.

Internal initiation of translation of five dendritically localized neuronal mRNAs.

Coinciding early activation of the human primary visual cortex and anteromedial cuneus.

Characteristics of glycine receptors expressed by embryonic rat brain mRNAs

Point mutant mice with hypersensitive alpha 4 nicotinic receptors show dopaminergic deficits and increased anxiety.

Morphological abnormalities in the brains of estrogen receptor beta knockout mice.

Theory for normal and impaired experience-dependent plasticity in neocortex of adult rats.

Tonic nicotinic modulation of serotoninergic transmission in the spinal cord.

Activity-dependent CREB phosphorylation: Convergence of a fast, sensitive calmodulin kinase pathway and a slow, less sensitive mitogen-activated protein kinase pathway

An orchestrated gene expression component of neuronal programmed cell death revealed by cDNA array analysis.

Localization and regulation of GLUTx1 glucose transporter in the hippocampus of streptozotocin diabetic rats.

In vivo evidence for a cochlear amplifier in the hair-cell bundle of lizards.

β-Neuregulin-1 is required for the in vivo development of functional $Ca^{2+}-activated$ $K^{+}$ channels in parasympathetic neurons

Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

Urocortin II: a member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors.

Brain 5alpha-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation.

Coupling of histamine $H_{3}$ receptors to neuronal $Na^{+}/H^{+}$ exchange: A novel protective mechanism in myocardial ischemia

Effects of nitric oxide-releasing aspirin versus aspirin on restenosis in hypercholesterolemic mice.

Ryanodine receptor point mutant E4032A reveals an allosteric interaction with ryanodine

Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta.

Calmodulin kinase is a molecular switch for cardiac excitation –contraction coupling

Defective trafficking and function of KATP channels caused by a sulfonylurea receptor 1 mutation associated with persistent hyperinsulinemic hypoglycemia of infancy.

Reconstitution and functional comparison of purified GlpF and AqpZ, the glycerol and water channels from Escherichia coli

Altered ubiquitination and stability of aquaporin-1 in hypertonic stress.

Galactose-extended glycans of antibodies produced by transgenic plants.

One ring or two? Determination of ring number in carotenoids by lycopene epsilon-cyclases.

Chlorophyll and carotenoid binding in a simple red algal light-harvesting complex crosses phylogenetic lines.

KAT1 is not essential for stomatal opening

Invariant scaling relationships for interspecific plant biomass production rates and body size.

Metapopulation extinction caused by mutation accumulation.

Lifespan depends on month of birth.

Year: 2001 Volume: 98 Issue: 4

Year: 2001 Volume: 98 Issue: 3

Year: 2001 Volume: 98 Issue: 2

Year: 2001 Volume: 98 Issue: 1

Year: 2000 Volume: 97

Year: 1999 Volume: 96

Year: 1998 Volume: 95

Year: 1997 Volume: 94

Year: 1996 Volume: 93

Year: 1995 Volume: 92

Year: 1994 Volume: 91

Year: 1993 Volume: 90

Year: 1992 Volume: 89

Year: 1991 Volume: 88

Year: 1990 Volume: 87

Year: 1989 Volume: 86

Year: 1988 Volume: 85

Year: 1987 Volume: 84

Year: 1986 Volume: 83

Year: 1985 Volume: 82

Year: 1984 Volume: 81

Year: 1983 Volume: 80

Year: 1982 Volume: 79

Year: 1981 Volume: 78

Year: 1980 Volume: 77

Year: 1979 Volume: 76

Year: 1978 Volume: 75

Year: 1977 Volume: 74

Year: 1976 Volume: 73

Year: 1975 Volume: 72

Year: 1974 Volume: 71

Year: 1973 Volume: 70

Year: 1972 Volume: 69

Year: 1971 Volume: 68

Year: 1970 Volume: 67

Year: 1970 Volume: 66

Year: 1970 Volume: 65

Year: 1969 Volume: 64

Year: 1969 Volume: 63

Year: 1969 Volume: 62

Year: 1968 Volume: 61

Year: 1968 Volume: 60

Year: 1968 Volume: 59

Year: 1967 Volume: 58

Year: 1967 Volume: 57

Year: 1966 Volume: 56

Year: 1966 Volume: 55

Theory for normal and impaired experience-dependent plasticity in neocortex of adult rats.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Armstrong-james, M. Ebner, F. F. Rema, V. Benusková, L.
Description	Author Affiliation: Benusková L ( Department of Computer Science and Engineering, Slovak Technical University, Ilkovicova 3, 812 19 Bratislava 1, Slovakia. benus@elf.stuba.sk);
Abstract	We model experience-dependent plasticity in the cortical representation of whiskers (the barrel cortex) in normal adult rats, and in adult rats that were prenatally exposed to alcohol. Prenatal exposure to alcohol (PAE) caused marked deficits in experience-dependent plasticity in a cortical barrel-column. Cortical plasticity was induced by trimming all whiskers on one side of the face except two. This manipulation produces high activity from the intact whiskers that contrasts with low activity from the cut whiskers while avoiding any nerve damage. By a computational model, we show that the evolution of neuronal responses in a single barrel-column after this sensory bias is consistent with the synaptic modifications that follow the rules of the Bienenstock, Cooper, and Munro (BCM) theory. The BCM theory postulates that a neuron possesses a moving synaptic modification threshold, theta(M), that dictates whether the neuron's activity at any given instant will lead to strengthening or weakening of its input synapses. The current value of theta(M) changes proportionally to the square of the neuron's activity averaged over some recent past. In the model of alcohol impaired cortex, the effective theta(M) has been set to a level unattainable by the depressed levels of cortical activity leading to 'impaired' synaptic plasticity that is consistent with experimental findings. Based on experimental and computational results, we discuss how elevated theta(M) may be related to (i) reduced levels of neurotransmitters modulating plasticity, (ii) abnormally low expression of N-methyl-d-aspartate receptors (NMDARs), and (iii) the membrane translocation of Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in adult rat cortex subjected to prenatal alcohol exposure.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	5
Volume Number	98
Language	English
Publisher	National Academy of Sciences
Publisher Date	2001-03-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Neocortex Physiology Neuronal Plasticity Action Potentials Animals Computer Simulation Models, Biological Physiopathology Research Support, Non-U.S. Gov't Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in