NDLI: Development of teeth in chick embryos after mouse neural crest transplantations.

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Development of teeth in chick embryos after mouse neural crest transplantations.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Mitsiadis, Thimios A. Fontaine-pérus, Josiane Sharpe, Paul Chéraud, Yvonnick
Description	Author Affiliation: Mitsiadis TA ( Department of Craniofacial Development, Guy's, King's, and St. Thomas' Dental Institute, King's College London, Floor 28 Guy's Tower, Guy's Hospital, United Kingdom.);
Abstract	Teeth were lost in birds 70-80 million years ago. Current thinking holds that it is the avian cranial neural crest-derived mesenchyme that has lost odontogenic capacity, whereas the oral epithelium retains the signaling properties required to induce odontogenesis. To investigate the odontogenic capacity of ectomesenchyme, we have used neural tube transplantations from mice to chick embryos to replace the chick neural crest cell populations with mouse neural crest cells. The mouse/chick chimeras obtained show evidence of tooth formation showing that avian oral epithelium is able to induce a nonavian developmental program in mouse neural crest-derived mesenchymal cells.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	11
Volume Number	100
Language	English
Publisher	National Academy of Sciences
Publisher Date	2003-05-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Nerve Tissue Transplantation Tooth Growth & Development Animals Chick Embryo Immunohistochemistry In Situ Hybridization Mice Research Support, Non-U.S. Gov't Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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