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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Fehren-schmitz, Lars O'fallon, Brendan D. |
| Spatial Coverage | Europe |
| Description | Author Affiliation: O'Fallon BD ( Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA. brendano@u.washington.edu); |
| Abstract | The genetic and demographic impact of European contact with Native Americans has remained unclear despite recent interest. Whereas archeological and historical records indicate that European contact resulted in widespread mortality from various sources, genetic studies have found little evidence of a recent contraction in Native American population size. In this study we use a large dataset including both ancient and contemporary mitochondrial DNA to construct a high-resolution portrait of the Holocene and late Pleistocene population size of indigenous Americans. Our reconstruction suggests that Native Americans suffered a significant, although transient, contraction in population size some 500 y before the present, during which female effective size was reduced by â ¼50%. These results support analyses of historical records indicating that European colonization induced widespread mortality among indigenous Americans. |
| ISSN | 00278424 |
| e-ISSN | 10916490 |
| Journal | Proceedings of the National Academy of Sciences of the United States of America |
| Issue Number | 51 |
| Volume Number | 108 |
| Language | English |
| Publisher | National Academy of Sciences |
| Publisher Date | 2011-12-01 |
| Publisher Place | United States |
| Access Restriction | Open |
| Subject Keyword | European Continental Ancestry Group Genetics Genetics, Population Indians, North American Bayes Theorem DNA, Mitochondrial Ethnic Groups Genetic Variation Models, Genetic Molecular Sequence Data Phylogeny Population Dynamics Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
| Subject | Multidisciplinary |
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