NDLI: Racial discrimination predicts greater systemic inflammation in pregnant African American women.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Giurgescu, Carmen Engeland, Christopher G. Templin, Thomas N. Zenk, Shannon N. Koenig, Mary Dawn Garfield, Lindsey
Description	Author Affiliation: Giurgescu C ( College of Nursing, Wayne State University, Detroit, MI, USA, 48202. Electronic address: carmen.giurgescu@wayne.edu.); Engeland CG ( Department of Biobehavioral Health and College of Nursing, Pennsylvania State University, University Park, PA, USA, 16802. Electronic address: cge2@psu.edu.); Templin TN ( College of Nursing, Wayne State University, Detroit, MI, USA, 48202. Electronic address: ac0410@wayne.edu.); Zenk SN ( College of Nursing, University of Illinois at Chicago, Chicago, IL, USA, 60612. Electronic address: szenk@uic.edu.); Koenig MD ( College of Nursing, University of Illinois at Chicago, Chicago, IL, USA, 60612. Electronic address: marydh@uic.edu.); Garfield L ( Marcella Niehoff School of Nursing, Loyola University, Chicago, IL, USA, 60660. Electronic address: lgarfield@luc.edu.)
Abstract	PURPOSE: Chronic exposure to racial discrimination by pregnant African American women may lead to allostatic overload; thereby, predisposing women to systemic inflammation. Thus, the goal of this study was to examine if experiences of racial discrimination are related to systemic inflammation in pregnant African Americans. METHODS: A sample of 96 African American women from Chicago completed questionnaires and had blood drawn during the second trimester of pregnancy (19.7±2.5 weeks). RESULTS: Experiences of racial discrimination were associated with higher cytokine levels of interleukin (IL)-4 (B=2.161, 95% CI = 1.02-3.30, p<.001) and IL-6 (B=1.859, 95% CI=.61-3.11, p=.004) when controlling for covariates. CONCLUSION: These findings suggest that experiences of racial discrimination may cause physiological wear and tear on the body leading to alteration of immune functions. Nurses should inquire about women's experiences of racial discrimination and make referrals for community or church support groups for women who report racial discrimination.
File Format	HTM / HTML
ISSN	08971897
Journal	Applied Nursing Research
Volume Number	32
e-ISSN	15328201
Language	English
Publisher	Elsevier
Publisher Date	2016-11-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Nursing
Content Type	Text
Resource Type	Article
Subject	Nursing

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