| Content Provider |
World Health Organization (WHO)-Global Index Medicus |
| Author |
Spatari, Giovanna Saitta, Salvatore Giorgianni, Concetto Cristani, Maria Teresa Quattrocchi, Paolina Abbate, Adriana Carrieri, Mariella Ferraro, Giorgia Saija, Antonella Gangemi, Sebastiano |
| Spatial Coverage |
Sicily |
| Description |
Country affiliation: Italy Author Affiliation: Spatari G ( Department of Social and Environmental Medicine, University of Messina, Messina, Italy.); Saitta S ( Department of Clinical and Experimental Medicine, School and Unit of Allergy and Clinical Immunology, University of Messina, Messina, Italy saittasalvatore@tiscalinet.it.); Giorgianni C ( Department of Social and Environmental Medicine, University of Messina, Messina, Italy.); Cristani MT ( Department Farmaco-Biologico, School of Pharmacy, University of Messina, Messina, Italy.); Quattrocchi P ( Department of Clinical and Experimental Medicine, School and Unit of Allergy and Clinical Immunology, University of Messina, Messina, Italy.); Abbate A ( Department of Social and Environmental Medicine, University of Messina, Messina, Italy.); Carrieri M ( Department of Environmental Medicine and Public Health, University of Padua, Padua, Italy.); Ferraro G ( Department of Clinical and Experimental Medicine, Fellow unit of Allergy and Clinical Immunology, University of Messina, Messina, Italy.); Saija A ( Department Farmaco-Biologico, School of Pharmacy, University of Messina, Messina, Italy.); Gangemi S ( Department of Clinical and Experimental Medicine, School and Unit of Allergy and Clinical Immunology, University of Messina, Messina, Italy Institute of Biomedicine and Molecular Immunology, National Research Council, Palermo, Italy.) |
| Abstract |
OBJECTIVE: To establish if serum levels of interleukin-10 (IL-10) in subjects exposed to benzene are connected with age, working years, and employment age. METHODS: We evaluated serum levels of IL-10 in 51 employees working in oil refinery (group A) and in 16 office workers who resided in the same area (group B). RESULTS: There was no statistically significant difference between serum concentrations of IL-10 in groups A and B. There was a statistically significant dependent relationship in group A between age, working years, and serum concentration of IL-10. There was a statistically significant and positive dependent relationship in group A between serum concentration of IL-10 and employment age. CONCLUSIONS: The role played by IL-10 in benzene immune suppression may be relevant and attention should be directed toward assessment of age, working years, and employment age in benzene-exposed populations. |
| File Format |
HTM / HTML |
| ISSN |
07482337 |
| Issue Number |
4 |
| Volume Number |
31 |
| e-ISSN |
14770393 |
| Journal |
Toxicology and Industrial Health |
| Language |
English |
| Publisher |
Sage Publications |
| Publisher Date |
2015-04-01 |
| Publisher Place |
Great Britain (UK) |
| Access Restriction |
One Nation One Subscription (ONOS) |
| Subject Keyword |
Discipline Occupational Medicine Discipline Toxicology Benzene Poisoning Interleukin-10 Blood Occupational Exposure Analysis Adult Age Factors Dose-response Relationship, Drug Extraction And Processing Industry Statistics & Numerical Data Humans Immune System Drug Effects Male Middle Aged Petroleum Sicily Journal Article Research Support, Non-u.s. Gov't |
| Content Type |
Text |
| Resource Type |
Article |
| Subject |
Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health Toxicology |
