NDLI: Evaluation of expression of the PTEN gene, oestrogen and progesterone receptors as diagnostic and predictive factors in endometrial cancer.

Please wait, while we are loading the content...

Clinical outcome of hematopoietic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL): experience from a single institution.

MCM3 protein expression in follicular and classical variants of papillary thyroid carcinoma.

MicroRNA-200c regulates the sensitivity of chemotherapy of gastric cancer SGC7901/DDP cells by directly targeting RhoE.

Apoptosis of human pancreatic carcinoma PC-2 cells by an antisense oligonucleotide specific to point mutated K-ras.

The incidence of EGFR-activating mutations in bone metastases of lung adenocarcinoma.

Polymorphism of UBC9 gene encoding the SUMO-E2-conjugating enzyme and breast cancer risk.

Prognostic significance of human papillomavirus (HPV) status and expression of selected markers (HER2/neu, EGFR, VEGF, CD34, p63, p53 and Ki67/MIB-1) on outcome after (chemo-) radiotherapy in patients with squamous cell carcinoma of uterine cervix.

Is minimal residual lymph node disease in papillary thyroid cancer of prognostic impact? An analysis of the epithelial cell adhesion molecule EpCAM in lymph nodes of 40 pN0 patients.

Analysis of clinicopathological features and prognostic factors of desmoplastic small round cell tumor.

Gelsolin and ceruloplasmin as potential predictive biomarkers for cervical cancer by 2D-DIGE proteomics analysis.

Internal Mammary Sentinel Node Biopsy in Breast Cancer. Is it Indicated?

Value of FDG-PET/CT examinations in different cancers of children, focusing on lymphomas.

BAP1 protein is a progression factor in malignant pleural mesothelioma.

Effectiveness and complications of anthracycline and taxane in the therapy of breast cancer: a meta-analysis.

MicroRNA expression profiles in Kaposi's sarcoma.

Evaluation of expression of the PTEN gene, oestrogen and progesterone receptors as diagnostic and predictive factors in endometrial cancer.

A new RNA-seq method to detect the transcription and non-coding RNA in prostate cancer.

Pathways enrichment analysis for differentially expressed genes in squamous lung cancer.

Xanthine oxido-reductase, free radicals and cardiovascular disease. A critical review.

The relationship between gastric cancer and Helicobacter pylori in formaldehyde fixed paraffin embedded gastric tissues of gastric cancer patients-scorpion real-time PCR assay findings.

New treatment options for lung adenocarcinoma--in view of molecular background.

Gliomatosis cerebri type 1 with extensive involvement of the spinal cord and BRAF V600E mutation.

Stimuli-induced organ-specific injury enhancement of organotropic metastasis in a spatiotemporal regulation.

Year: 2013 Volume: 19

Year: 2012 Volume: 18

Year: 2011 Volume: 17

Year: 2010 Volume: 16

Year: 2009 Volume: 15

Year: 2008 Volume: 14

Year: 2007 Volume: 13

Year: 1997 Volume: 3

Evaluation of expression of the PTEN gene, oestrogen and progesterone receptors as diagnostic and predictive factors in endometrial cancer.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Samulak, Dariusz Grosman-Dziewiszek, Patrycja Michalska, Magdalena M. Mojs, Ewa Samulak, Katarzyna Romanowicz, Hanna Smolarz, Beata
Description	Country affiliation: Poland Author Affiliation: Samulak D ( Cathedral of Mother's and Child's Health, Poznan University of Medical Sciences, ul. Polna 33, 60-535, Poznan, Poland.)
Abstract	Endometrial cancer belongs to the commonest malignancy in females after breast cancer, malignant neoplasm of female genitals in Europe and North America but there is still not significant improvement as far as the curability of this neoplasm is concerned, especially its advanced forms. That is why there is need to define new factors that could be not only diagnostic but also predictve factors. In present study we analyzed the mRNA PTEN expression by quantitative real-time polymerase chain reaction (Q-PCR) in 123 women of endometrial carcinoma and 14 women of control group. Moreover we assessed oestrogen (ER) and progesterone receptors (PgR) in all cases. We defined the correlation between expression of PTEN gene and receptors and between PTEN expression and maturity grade of cancer. Neoplasm advancement grade G1 was diagnosed in 82.11% of patients (n = 101), G2 in 9.76% of patients (n = 12) and G3 in 8.13% of patients (n = 10). Presence of ER and PgR and decreased expression of PTEN gene was found in majority of patients with endometrial cancer (79.12% and 59.34% respectively) and the most numerous group was with weak expression of ER and strong expression of PgR. There was no statistically significant difference in gene expression depending on receptors expression nor maturity grade of cancer (p > 0.05). Evaluation of expression of PTEN gene may turn out to be a very useful tool aimed at qualifying patients for different therapies of endometrial cancer and at searching of new diagnostic and therapeutic methods of this cancer independently on its receptor status nor maturity grade of cancer.
File Format	HTM / HTML
ISSN	12194956
e-ISSN	15322807
DOI	10.1007/s12253-013-9684-3
Journal	Pathology & Oncology Research
Issue Number	1
Volume Number	20
Language	English
Publisher	Springer
Publisher Date	2014-01-01
Publisher Place	Netherlands
Access Restriction	Open
Subject Keyword	Discipline Oncology Endometrial Neoplasms Diagnosis Genetics Pten Phosphohydrolase Receptors, Estrogen Receptors, Progesterone Case-control Studies Metabolism Pathology Gene Expression Neoplasm Staging Biosynthesis
Content Type	Text
Resource Type	Article
Subject	Cancer Research Pathology and Forensic Medicine Oncology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Evaluation of Expression of the PTEN Gene, Oestrogen and Progesterone Receptors as Diagnostic and Predictive Factors in Endometrial Cancer

Initial experience with the Oncotype DX assay in decision-making for adjuvant therapy of early oestrogen receptor-positive breast cancer in Hong Kong.

Expression of PTTG1 and PTEN in endometrial carcinoma: correlation with tumorigenesis and progression.

The relationship of COX-2 expression with estrogen receptor, progesterone receptor and prognostic parameters in endometrial carcinomas.

Evaluation of clinicopathological characteristics and oestrogen receptor gene expression in oestrogen receptor-negative, progesterone receptor-positive canine mammary carcinomas.

Heparanase expression increases throughout the endometrial hyperplasia-cancer sequence.

Dietary vitamin D exposure prevents obesity-induced increase in endometrial cancer in Pten+/- mice.

Relationship between epidemiologic risk factors and hormone receptor expression in ovarian cancer: results from the Nurses' Health Study.

Prognostic factors in patients with metastatic breast cancer at the time of diagnosis.

Evaluation of expression of the PTEN gene, oestrogen and progesterone receptors as diagnostic and predictive factors in endometrial cancer.

Similar Documents

Evaluation of Expression of the PTEN Gene, Oestrogen and Progesterone Receptors as Diagnostic and Predictive Factors in Endometrial Cancer

Initial experience with the Oncotype DX assay in decision-making for adjuvant therapy of early oestrogen receptor-positive breast cancer in Hong Kong.

Expression of PTTG1 and PTEN in endometrial carcinoma: correlation with tumorigenesis and progression.

The relationship of COX-2 expression with estrogen receptor, progesterone receptor and prognostic parameters in endometrial carcinomas.

Evaluation of clinicopathological characteristics and oestrogen receptor gene expression in oestrogen receptor-negative, progesterone receptor-positive canine mammary carcinomas.

Heparanase expression increases throughout the endometrial hyperplasia-cancer sequence.

Dietary vitamin D exposure prevents obesity-induced increase in endometrial cancer in Pten+/- mice.

Relationship between epidemiologic risk factors and hormone receptor expression in ovarian cancer: results from the Nurses' Health Study.

Prognostic factors in patients with metastatic breast cancer at the time of diagnosis.

Evaluation of expression of the PTEN gene, oestrogen and progesterone receptors as diagnostic and predictive factors in endometrial cancer.