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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Billiet, Thomas Van Gasse, Bjorn Gevaert, Elien Cornelissen, Maria Martins, José C. Dubruel, Peter |
| Description | Country affiliation: Belgium Author Affiliation: Billiet T ( Polymer Chemistry & Biomaterials Research Group, Ghent University, Krijgslaan 281 S4 Bis, Ghent, 9000, Belgium.) |
| Abstract | The synthesis and evaluation of gelatin acrylamide as an alternative to the well-established gelatin methacrylamide are reported. High-resolution magic angle spinning NMR is used for the quantitative determination of the chemical cross-linking density. The gelatin acrylamide precursors reveal enhanced cross-linking in terms of reactivity and double bond conversion, resulting in stronger networks. Remarkably, even at very low double bond conversions, ≈5%, gel fractions of ≈40% are obtained. The cross-linked networks are also reviewed in the framework of the rubber elasticity and thermodynamic swelling theories to estimate important nanostructural properties. Preliminary cell tests revealed that highly viable (>90%) cell-laden constructs are obtained. |
| File Format | HTM / HTML |
| ISSN | 16165187 |
| Issue Number | 11 |
| Volume Number | 13 |
| e-ISSN | 16165195 |
| Journal | Macromolecular Bioscience |
| Language | English |
| Publisher | Wiley-VCH |
| Publisher Date | 2013-11-01 |
| Publisher Place | Germany |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Biochemistry Acrylamide Chemistry Acrylamides Biocompatible Materials Gelatin Hydrogels Animals Pharmacology Radiation Effects Cattle Cell Survival Drug Effects Cells, Immobilized Elasticity Hep G2 Cells Humans Light Magnetic Resonance Spectroscopy Methods Materials Testing Photochemical Processes Polymerization Spectroscopy, Fourier Transform Infrared Thermodynamics Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Materials Chemistry Biomaterials Bioengineering Biotechnology Polymers and Plastics |
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