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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Erman, Andreja Jezernik, Kristijan |
| Description | Country affiliation: Slovenia Author Affiliation: Erman A ( Institute of Cell Biology, Medical Faculty, Lipiceva 2 1000 Ljubljana, Slovenia, Slovenia.); Jezernik K ( Institute of Cell Biology, Medical Faculty, Lipiceva 2 1000 Ljubljana, Slovenia, Slovenia.) |
| Abstract | The purpose of this work was to investigate proliferation and differentiation of the mouse urothelial cells from the day of birth until the 5 postnatal day. The expression of proliferating cell nuclear antigen (PCNA) was studied immunocytochemically and the differentiation of apical plasma membrane of superficial cells was analysed by scanning microscopy. It was established that proliferation activity is very high during all five days since PCNA positive cells are seen in the superficial and in basal cell layer of the urothelium. Results of scanning microscopy show that the differentiation of superficial urothelial cells is a nonsynchronous process, which gradually progresses from the day of birth and leads into homogeneous population of terminally differentiated superficial cells on the 5 postnatal day. |
| File Format | HTM / HTML |
| ISSN | 00316768 |
| Issue Number | Suppl 1 |
| Journal | Pflügers Archiv - European Journal of Physiology |
| Volume Number | 440 |
| e-ISSN | 14322013 |
| Language | English |
| Publisher | Springer |
| Publisher Date | 2000-01-01 |
| Publisher Place | Germany |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Physiology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physiology Physiology (medical) Clinical Biochemistry |
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