NDLI: Premenstrual asthma: prevalence, cycle-to-cycle variability and relationship to oral contraceptive use and menstrual symptoms.

Please wait, while we are loading the content...

Premenstrual asthma: prevalence, cycle-to-cycle variability and relationship to oral contraceptive use and menstrual symptoms.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Murphy, Vanessa E. Gibson, Peter G.
Spatial Coverage	Australia
Description	Country affiliation: Australia Author Affiliation: Murphy VE ( Centre for Asthma and Respiratory Diseases, University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia. vanessa.murphy@newcastle.edu.au)
Abstract	The prevalence of asthma is higher in women than men of reproductive age and almost half of all hospitalisations for asthma in women occur during the perimenstrual phase of the cycle. The mechanisms of premenstrual asthma (PMA) are unknown and a definition of PMA has not been clearly presented in the literature. The objective of this study was to determine the prevalence of PMA using a variety of definitions, to investigate the cycle-to-cycle variation in PMA, the effects of oral contraceptive use and the relationship between PMA and premenstrual symptoms. Premenopausal women with asthma (n = 28) were prospectively followed for at least 12 weeks over 2-4 consecutive menstrual cycles. Asthma symptoms, beta(2)-agonist and inhaled corticosteroid use and morning and evening peak expiratory flow were recorded daily. The following types of PMA definitions were investigated: self-reported PMA, increased symptoms, increased medication use, decreased peak flow or a combination of changes in symptoms, medication and peak flow. Changes of more than 20%, for at least 2 consecutive days of the luteal phase (last 14 days of the cycle prior to menstruation) compared to the early follicular phase average (first 7 days after menstruation) were considered PMA. Using a composite definition where subjects experienced increased symptoms and medication use with or without a change in peak flow, 16 subjects were classified as having PMA (57%), while 12 did not have PMA. Only 4 subjects (25%) had PMA in every cycle examined. Fifty-five percent of subjects who used oral contraceptives had PMA, while 59% of subjects who did not use oral contraceptives had PMA. Women who were defined PMA using the composite definition were more likely than those without PMA to experience a 20% decrease in peak flow during the luteal phase. There was no relationship between asthma symptoms and premenstrual symptoms on day 1 of the menstrual cycle in women with PMA. PMA resulting in increased symptoms and medication use occurred in 57% of subjects studied for 2-4 menstrual cycles. The use of oral contraceptives is not protective and further work is required to elucidate the mechanisms of PMA.
File Format	HTM / HTML
ISSN	02770903
Issue Number	8
Volume Number	45
e-ISSN	15324303
Journal	Journal of Asthma
Language	English
Publisher	Taylor & Francis
Publisher Date	2008-10-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Pulmonology Asthma Epidemiology Contraceptives, Oral Administration & Dosage Menstrual Cycle Physiology Adult Anti-asthmatic Agents Therapeutic Use Area Under Curve Drug Therapy Australia Cohort Studies Female Humans Middle Aged Peak Expiratory Flow Rate Prevalence Statistics, Nonparametric Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Pulmonary and Respiratory Medicine Immunology and Allergy Pediatrics, Perinatology and Child Health

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Premenstrual asthma and symptoms related to premenstrual syndrome.

Hormonal contraceptive use and prevalence of premenstrual symptoms in a multiethnic Canadian population

The relationship between changes in peak expiratory flow and asthma exacerbations in asthmatic children

Premenstrual symptoms and syndrome according to age at menarche in a 1982 birth cohort in southern Brazil

Influence of menstrual cycle and hormonal contraceptive use on MS symptom fluctuations: A pilot study.

Menstrual manipulation: options for suppressing the cycle.

Effects of oral contraceptives on spatial cognition depend on pharmacological properties and phase of the contraceptive cycle

The Role of Oral Contraceptive Pills in Hidradenitis Suppurativa: A Cohort Study

Behcet's disease: remission of patient symptoms after oral contraceptive therapy.

Premenstrual asthma: prevalence, cycle-to-cycle variability and relationship to oral contraceptive use and menstrual symptoms.

Similar Documents

Premenstrual asthma and symptoms related to premenstrual syndrome.

Hormonal contraceptive use and prevalence of premenstrual symptoms in a multiethnic Canadian population

The relationship between changes in peak expiratory flow and asthma exacerbations in asthmatic children

Premenstrual symptoms and syndrome according to age at menarche in a 1982 birth cohort in southern Brazil

Influence of menstrual cycle and hormonal contraceptive use on MS symptom fluctuations: A pilot study.

Menstrual manipulation: options for suppressing the cycle.

Effects of oral contraceptives on spatial cognition depend on pharmacological properties and phase of the contraceptive cycle

The Role of Oral Contraceptive Pills in Hidradenitis Suppurativa: A Cohort Study

Behcet's disease: remission of patient symptoms after oral contraceptive therapy.

Premenstrual asthma: prevalence, cycle-to-cycle variability and relationship to oral contraceptive use and menstrual symptoms.