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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Weitz, Marcus Licht, Christoph Müller, Mark Haber, Peter |
| Description | Author Affiliation: Weitz M ( University of Tuebingen, Department of Pediatrics, Hoppe-Seyler-Strasse 1, 72076 Tübingen, Germany. Electronic address: marcus.weitz@med.uni-tuebingen.de.) |
| Abstract | OBJECTIVE: Renal scintigraphy represents the current diagnostic standard to assess split kidney function. We tested the hypothesis that the relative renal volume assessed by ultrasound provides an equally reliable but less invasive tool for assessment of kidney function as compared to renal scintigraphy in patients with primary vesicoureteral reflux. METHODS: Renal ultrasound and renal scintigraphy were performed in 85 patients (median age 4.5 years, range 0.25-7.7) and repeated in 74 patients after 2-13 months (mean 7) of the primary investigation. Renal size was measured by ultrasound, and relative renal volume was calculated for each kidney by using the formula of a prolate ellipsoid. Renal function was estimated for each side (split renal function) by scintigraphy with (99m)Tc MAG3. RESULTS: The mean difference between relative renal volume measured by ultrasound and split renal function determined by renal scintigraphy was 2.8% (standard deviation ± 4.1%; 95% confidence interval 10.8/-5.2%). There was a statistically significant correlation between relative renal volume estimated by ultrasound and split renal function estimated by renal scintigraphy at first examination (r = 0.98; p < 0.001) and at follow-up (r = 0.91; p < 0.001). CONCLUSION: We conclude that ultrasound measurement of relative renal volume is capable of assessing split renal function in children with primary vesicoureteral reflux and, thus, should be considered instead of the more invasive MAG3 scintigraphy. |
| File Format | HTM / HTML |
| ISSN | 14775131 |
| Part | Pt B |
| Volume Number | 9 |
| e-ISSN | 18734898 |
| Journal | Journal of Pediatric Urology |
| Issue Number | 6 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2013-12-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Urology Discipline Pediatrics Kidney Function Tests Methods Ultrasonography Vesico-ureteral Reflux Child Child, Preschool Female Follow-up Studies Humans Infant Kidney Physiopathology Male Radionuclide Imaging Retrospective Studies Sensitivity And Specificity Technetium Tc 99m Mertiatide Congenital Comparative Study Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Urology Pediatrics, Perinatology and Child Health |
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