NDLI: Microstructure and in vitro behaviour of 45S5 bioglass coatings deposited by high velocity suspension flame spraying (HVSFS).

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Altomare, L. Bellucci, D. Bolelli, G. Bonferroni, B. Cannillo, V. De Nardo, L. Gadow, R. Killinger, A. Lusvarghi, L. Sola, A. Stiegler, N.
Description	Country affiliation: Italy Author Affiliation: Altomare L ( Dipartimento di Chimica, Materiali e Ingegneria Chimica G. Natta, Politecnico di Milano, Via Mancinelli 7, 20131, Milan, Italy.)
Abstract	The high-velocity suspension flame spraying technique (HVSFS) was employed in order to deposit 45S5 bioactive glass coatings onto titanium substrates, using a suspension of micron-sized glass powders dispersed in a water + isopropanol mixture as feedstock. By modifying the process parameters, five coatings with different thickness and porosity were obtained. The coatings were entirely glassy but exhibited a through-thickness microstructural gradient, as the deposition mechanisms of the glass droplets changed at every torch cycle because of the increase in the system temperature during spraying. After soaking in simulated body fluid, all of the coatings were soon covered by a layer of hydroxyapatite; furthermore, the coatings exhibited no cytotoxicity and human osteosarcoma cells could adhere and proliferate well onto their surfaces. HVSFS-deposited 45S5 bioglass coatings are therefore highly bioactive and have potentials as replacement of conventional hydroxyapatite in order to favour osseointegration of dental and prosthetic implants.
File Format	HTM / HTML
ISSN	09574530
Issue Number	5
Volume Number	22
e-ISSN	15734838
Journal	Journal of Materials Science: Materials in Medicine
Language	English
Publisher	Springer
Publisher Date	2011-05-01
Publisher Place	United States
Access Restriction	Subscribed
Subject Keyword	Discipline Biomedical Engineering Biocompatible Materials Chemistry Ceramics Body Fluids Cell Line, Tumor Durapatite Humans Joint Prosthesis Microscopy, Electron, Scanning Surface Properties Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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