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Spontaneous recovery from progressive multifocal leukoencephalopathy in a patient with non-active sarcoidosis.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Goldbecker, Annemarie Tountopoulou, Argyro Wurster, Ulrich Donnerstag, Frank Brandis, Almuth Bonnemann, Catharina Weissenborn, Karin
Description	Country affiliation: Germany Author Affiliation: Goldbecker A ( Department of Neurology and Neurophysiology, Hannover Medical School, Carl-Neuberg Strasse 1, Hannover, Germany. goldbecker.annemarie@mh-hannover.de)
Abstract	We report the case of a 50-year-old female patient with non-active sarcoidosis and no kind of immunosuppression, admitted to our hospital because of increasing confusion and focal neurological deficits. Initially a tumor, herpes encephalitis, or neurosarcoidosis were suspected, but surprisingly biopsy revealed progressive multifocal leukoencephalopathy, additionally confirmed by JC-positive PCR in cerebrospinal fluid. Cases of sarcoidosis and progressive multifocal leukoencephalopathy have been reported before. This is the first case of a patient with no sign of active sarcoidosis and without immunosuppressive therapy who recovered spontaneously with a follow-up time of nearly 3 years.
File Format	HTM / HTML
ISSN	12019712
e-ISSN	18783511
Journal	International Journal of Infectious Diseases
Issue Number	Suppl 3
Volume Number	14
Language	English
Publisher	Elsevier
Publisher Date	2010-09-01
Publisher Place	Canada
Access Restriction	Open
Subject Keyword	Discipline Communicable Diseases Leukoencephalopathy, Progressive Multifocal Complications Sarcoidosis Benzodiazepines Therapeutic Use Brain Pathology Diagnosis Drug Therapy Magnetic Resonance Imaging Remission, Spontaneous Serotonin Uptake Inhibitors
Content Type	Text
Resource Type	Case study Article
Subject	Infectious Diseases Microbiology (medical)

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