NDLI: Surveillance of hospitalized and outpatient cases of pertussis in Catalonia from 2003 to 2009.

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Surveillance of hospitalized and outpatient cases of pertussis in Catalonia from 2003 to 2009.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Crespo Fernández, Inma Soldevila, Núria Carmona, Gloria Sala, Maria Rosa Godoy, Pere Domínguez, Angela
Spatial Coverage	Spain
Description	Country affiliation: Spain Author Affiliation: Crespo Fernández I ( CIBER Epidemiology and Public Health)
Abstract	Pertussis is a vaccine-preventable disease that generates a large number of cases and hospitalizations. In Catalonia, the vaccination schedule includes three doses of vaccine at 2, 4 and 6 mo and two booster doses at 18 mo and 4-6 y. In 2002, DTPw was replaced by DTPa. The aim of this study was to determine how the vaccination status affects pertussis hospitalizations. Cases were obtained from the epidemiological surveillance system of the Generalitat of Catalonia from 2003 to 2009. Hospitalization, immunization status and type of vaccine received in reported cases were analyzed. OR and 95% confidence intervals (CI) were calculated. To control the effect of age (< 6 mo and ≥ 6 mo) Mantel-Haenszel OR (ORMH) were calculated; statistical significance was established as p < 0.05. During the study period, 1538 cases were reported. Cases below vaccination age (< 2 mo) were excluded. A total of 265 cases were hospitalized: 137 (51.7%) had no vaccine administrated, 104 (39.2%) were correctly vaccinated according to age and 24 (9.1%) were poorly vaccinated. Correct vaccination protected against hospitalization (ORMH: 0.33; 95%CI: 0.23-0.47). Of hospitalized cases, 38 (14.3%) had received DTPw and 91 (34.2%) DTPa. Both vaccines were effective in avoiding hospitalization, and comparison showed no differences (ORMH: 0.73; 95%CI: 0.46-1.14). We highlight the importance of a correct follow-up immunization schedule in reducing the number of cases and hospitalizations.
File Format	HTM / HTML
ISSN	21645515
e-ISSN	2164554X
Journal	Human Vaccines & Immunotherapeutics
Issue Number	3
Volume Number	9
Language	English
Publisher	Taylor & Francis
Publisher Date	2013-03-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Immunology Discipline Therapeutics Epidemiological Monitoring Whooping Cough Epidemiology Adolescent Ambulatory Care Child, Preschool Diphtheria-tetanus-pertussis Vaccine Administration & Dosage Immunology Diphtheria-tetanus-acellular Pertussis Vaccines Hospitalization Statistics & Numerical Data Immunization Schedule Infant Spain Vaccination Utilization Prevention & Control Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Immunology and Allergy Immunology Pharmacology

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