NDLI: Open-label, prospective, randomized comparison of propofol and sevoflurane for laryngeal mask anesthesia for magnetic resonance imaging in pediatric patients.

Please wait, while we are loading the content...

Comparative bioavailability of single-dose methylphenidate from a multilayer-release bead formulation and an osmotic system: a two-way crossover study in healthy young adults.

Analgesic effectiveness of celecoxib and diclofenac in patients with osteoarthritis of the hip requiring joint replacement surgery: a 12-week, multicenter, randomized, double-blind, parallel-group, double-dummy, noninferiority study.

Effects of fluvastatin extended-release (80 mg) alone and in combination with ezetimibe (10 mg) on low-density lipoprotein cholesterol and inflammatory parameters in patients with primary hypercholesterolemia: a 12-week, multicenter, randomized, open-label, parallel-group study.

Comparison of the effects of doxazosin and atenolol on target organ damage in adults with type 2 diabetes mellitus and hypertension in the CARDHIAC study: a 9-month, prospective, randomized, open-label, blinded-evaluation trial.

Ambulatory blood pressure-lowering effects of valsartan and enalapril after a missed dose in previously untreated patients with hypertension: a prospective, randomized, open-label, blinded end-point trial.

A case-control study of the association between polymorphisms of the endothelial nitric oxide synthase and glycoprotein IIIa genes and upper gastrointestinal bleeding in users of low-dose aspirin.

Two single-center, double-blind, randomized, placebo-controlled, phase I studies to investigate the tolerability and pharmacokinetics of CH-1504, an antifolate, in healthy male subjects.

Colistin serum concentrations after intravenous administration in critically ill patients with serious multidrug-resistant, gram-negative bacilli infections: a prospective, open-label, uncontrolled study.

Risk factors for hyperglycemia in hospitalized adults receiving gatifloxacin: a retrospective, nested case-controlled analysis.

How Connecticut primary care physicians view treatments for streptococcal and nonstreptococcal pharyngitis.

Topical amethocaine gel 4% for intramuscular injection in term neonates: a double-blind, placebo-controlled, randomized trial.

Open-label, prospective, randomized comparison of propofol and sevoflurane for laryngeal mask anesthesia for magnetic resonance imaging in pediatric patients.

Donepezil use in children and adolescents with tics and attention-deficit/hyperactivity disorder: an 18-week, single-center, dose-escalating, prospective, open-label study.

Alzheimer's disease: the specter of fragmented policy and financing.

Cardiovascular outcomes among patients newly initiating atorvastatin or simvastatin therapy: a large database analysis of managed care plans in the United States.

Use of darbepoetin alfa and epoetin alfa in clinical practice in patients with cancer-related anemia.

The effects of direct-to-consumer advertising of statins on the attainment of low-density lipoprotein cholesterol goals.

Year: 2008 Volume: 30 Issue: Supplementary C

Year: 2008 Volume: 30 Spec No

Year: 2008 Volume: 30 Pt 2

Year: 2007 Volume: 29

Open-label, prospective, randomized comparison of propofol and sevoflurane for laryngeal mask anesthesia for magnetic resonance imaging in pediatric patients.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Kol, Iclal Ozdemir Egilmez, Hulusi Kaygusuz, Kenan Gursoy, Sinan Mimaroglu, Caner
Description	Country affiliation: Turkey Author Affiliation: Kol IO ( Department of Anesthesiology, Cumhuriyet University School of Medicine, Sivas, Turkey. driclal@gmail.com)
Abstract	BACKGROUND: Magnetic resonance imaging (MRI) for pediatric patients often requires deep sedation or anesthesia because they must remain completely immobile for a relatively long period to obtain high-quality images. OBJECTIVE: The aim of this study was to compare the effectiveness of propofol i.v. or inhalation of sevoflurane anesthesia with the laryngeal mask airway (LMA) for children undergoing MRI. METHODS: Children aged 2 to 6 years with American Society of Anesthesiologists' physical status of I to II who were scheduled for MRI were enrolled in this study and randomly divided into 2 groups. The propofol group was administered propofol 4 mg/kg i.v. followed by infusion of 150 microg/kg x min(-1). Patients in the sevoflurane group were induced with sevoflurane 8% by face mask and maintained with an air/oxygen mixture followed by sevoflurane 1.5%. Data recorded included age, weight, scan time, LMA insertion, removal, and recovery times, hemodynamic parameters, complications, pediatric anesthesia emergence delirium (PAED) scale score, child movement, and MRI interruption. A higher PAED score indicated a higher level of delirium. RESULTS: Eighty-eight children were enrolled and randomized to treatment. Nine children were excluded from analysis due to protocol violations. After completion of the study, there were 37 children in the propofol group (male/female, 18/19; mean [SD] age, 42.1 months; weight, 15.2 [4.9] kg; scan time, 20.5 [4.6] min) and 42 in the sevoflurane group (male/female, 15/27; mean [SD] age, 44.4 [26.1] months; weight, 15.1 [5.2] kg; scan time, 20.6 [4.8] min). No significant differences were found between the study groups with regard to age, weight, scan time, and hemodynamic parameters at baseline and during the study period. Mean LMA insertion, removal, and recovery times were significantly longer in the propofol group (4.8, 5.2, and 8.8 minutes, respectively) than in the sevoflurane group (3.3, 2.5, and 3.9 minutes, respectively) (P < 0.05). The mean PAED score in the propofol group was significantly lower than that in the sevoflurane group (mean [SD], 6.1 [4.0] vs 10.5 [3.7]; P < 0.05). The percentage of MRI interruption in the propofol group was significantly higher than that in the sevoflurane group (4 [11%] vs 0, respectively; P < 0.05). No episodes of hypotension or bradycardia occurred during the study, and alterations in the propofol infusion rate or sevoflurane concentration were not necessary. One child vomited in the sevoflurane group during the postoperative period. CONCLUSIONS: This small study found that sevoflurane, at the doses used in this study, provided shorter induction and faster recovery times than i.v. propofol for LMA anesthesia in these selected children undergoing MRI. The percentage of MRI interruption in the propofol group was significantly higher than that in the sevoflurane group. Sevoflurane was associated with a significantly higher score on the PAED scale, indicating greater emergence delirium.
File Format	HTM / HTML
ISSN	01492918
Issue Number	1
Volume Number	30
e-ISSN	1879114X
Journal	Clinical Therapeutics
Language	English
Publisher	Elsevier
Publisher Date	2008-01-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Pharmacology Anesthetics, General Therapeutic Use Immobilization Methods Magnetic Resonance Imaging Methyl Ethers Propofol Anesthesia Recovery Period Child Child, Preschool Delirium Diagnosis Female Humans Laryngeal Masks Male Prospective Studies Time Factors Journal Article Randomized Controlled Trial Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Pharmacology Pharmacology (medical)

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Intranasal dexmedetomidine premedication reduces minimum alveolar concentration of sevoflurane for laryngeal mask airway insertion and emergence delirium in children: a prospective, randomized, double-blind, placebo-controlled trial.

Efficacy of different concentrations of sevoflurane administered through a face mask for magnetic resonance imaging in children.

Propofol-remifentanil or sevoflurane for children undergoing magnetic resonance imaging? A randomised study.

Transition to propofol after sevoflurane anesthesia to prevent emergence agitation: a randomized controlled trial.

Emergence delirium in children: a randomized trial to compare total intravenous anesthesia with propofol and remifentanil to inhalational sevoflurane anesthesia.

Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.

Propofol anesthesia for children undergoing magnetic resonance imaging: a comparison with isoflurane, nitrous oxide, and a laryngeal mask airway.

Postoperative analgesia in children after propofol versus sevoflurane anesthesia.

A comparison of the duration and quality of recovery from isoflurane, sevoflurane and desflurane anaesthesia in dogs undergoing magnetic resonance imaging.

Open-label, prospective, randomized comparison of propofol and sevoflurane for laryngeal mask anesthesia for magnetic resonance imaging in pediatric patients.

Similar Documents

Intranasal dexmedetomidine premedication reduces minimum alveolar concentration of sevoflurane for laryngeal mask airway insertion and emergence delirium in children: a prospective, randomized, double-blind, placebo-controlled trial.

Efficacy of different concentrations of sevoflurane administered through a face mask for magnetic resonance imaging in children.

Propofol-remifentanil or sevoflurane for children undergoing magnetic resonance imaging? A randomised study.

Transition to propofol after sevoflurane anesthesia to prevent emergence agitation: a randomized controlled trial.

Emergence delirium in children: a randomized trial to compare total intravenous anesthesia with propofol and remifentanil to inhalational sevoflurane anesthesia.

Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.

Propofol anesthesia for children undergoing magnetic resonance imaging: a comparison with isoflurane, nitrous oxide, and a laryngeal mask airway.

Postoperative analgesia in children after propofol versus sevoflurane anesthesia.

A comparison of the duration and quality of recovery from isoflurane, sevoflurane and desflurane anaesthesia in dogs undergoing magnetic resonance imaging.

Open-label, prospective, randomized comparison of propofol and sevoflurane for laryngeal mask anesthesia for magnetic resonance imaging in pediatric patients.