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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Pedersen, N. A. Jensen, A. G. Kilmose, L. Olsen, K. S. |
| Description | Country affiliation: Denmark Author Affiliation: Pedersen NA ( Department of Anaesthesiology, University of Copenhagen, Glostrup Hospital, Glostrup, Denmark. niels.anker.pedersen@regionh.dk) |
| Abstract | BACKGROUND: Magnetic resonance imaging (MRI) of children is generally performed under sedation or with general anaesthesia (GA), but the ideal regimen has not been found. The aim of this study was to see if propofol-remifentanil would be a suitable alternative for the maintenance of anaesthesia in this category of patients. PATIENTS AND METHODS: Children aged 1-10 years, American Society of Anesthesiologists physical status 1-2 were included. After induction with thiopental or sevoflurane, the children were randomised to maintenance of anaesthesia with an infusion of propofol and remifentanil (group PR) (56 µg/kg/min of propofol and 0.06 µg/kg/min of remifentanil) or with sevoflurane 1.3 MAC (group S). A binasal catheter was placed in group PR and a laryngeal mask airway in group S. The children breathed spontaneously. The Paediatric Anaesthesia Emergence Delirium (PAED) score (primary end point), the number of movements during MRI, and the length of stay in the recovery room (secondary endpoints) were recorded. RESULTS: Sixty children were included in each group. A lower level of emergence delirium (measured as a lower PAED score) was found in group PR compared with group S, and the children in group PR were discharged earlier from the recovery room than the children in group S. However, 15 children in group PR vs. 0 in group S moved during the scan (P < 0.001). CONCLUSION: The PR infusion ensured a satisfactory stay in the recovery room, but additional boluses were necessary during the MRI. Sevoflurane was reliable during the MRI, but emergence delirium was a concern. |
| File Format | HTM / HTML |
| ISSN | 00015172 |
| Issue Number | 8 |
| Volume Number | 57 |
| e-ISSN | 00015172 |
| Journal | Acta Anaesthesiologica Scandinavica |
| Language | English |
| Publisher | Wiley |
| Publisher Date | 2013-09-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Anesthesiology Anesthetics, Inhalation Hypnotics And Sedatives Magnetic Resonance Imaging Methods Methyl Ethers Piperidines Propofol Anesthesia Recovery Period Child Child, Preschool Delirium Chemically Induced Epidemiology Double-blind Method Endpoint Determination Female Humans Infant Male Monitoring, Physiologic Movement Drug Effects Patient Satisfaction Sample Size Treatment Outcome Journal Article Randomized Controlled Trial |
| Content Type | Text |
| Resource Type | Article |
| Subject | Anesthesiology and Pain Medicine |
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