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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Haga, Henning A. Ranheim, Birgit Spadavecchia, Claudia |
| Description | Country affiliation: Norway Author Affiliation: Haga HA ( Department of Companion Animal Clinical Sciences, Norwegian School of Veterinary Science, Oslo, Norway. andreas.haga@veths.no) |
| Abstract | This study compared the effects of isoflurane in pigs (n=10 Yorkshire-Landrace cross) and dairy goats (n=10) by evaluation of electroencephalographic (EEG) burst suppression thresholds (BST) in the cerebral cortex and minimum alveolar concentration (MAC) values in the spinal cord. The study also investigated whether individual MAC values can predict the effects of isoflurane on the cerebral cortex. MAC values and BST/MAC ratios were significantly different between species. Inhibition of movement by isoflurane may be less effective in pigs than in goats. No significant correlation was found between individual MAC and BST values, indicating that in single animals the individual MAC poorly reflects the cerebrocortical depressant effect of isoflurane in pigs and goats. |
| File Format | HTM / HTML |
| ISSN | 10900233 |
| Issue Number | 2 |
| Volume Number | 187 |
| e-ISSN | 15322971 |
| Journal | The Veterinary Journal |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2011-02-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Anesthetics, Inhalation Comparative Study Goats Species Specificity Discipline Veterinary Medicine Cerebral Cortex Male Pharmacology Electroencephalography Metabolism Drug Effects Isoflurane Journal Article Animals Spinal Cord Swine Pulmonary Alveoli Female Physiology Veterinary Pharmacokinetics Anesthesia, Inhalation |
| Content Type | Text |
| Resource Type | Article |
| Subject | Veterinary Animal Science and Zoology |
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