NDLI: A planning target volume margin formula for hypofractionated intracranial stereotactic radiotherapy under cone beam CT image guidance with a six-degrees-of-freedom robotic couch and a mouthpiece-assisted mask system: a preliminary study.

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A planning target volume margin formula for hypofractionated intracranial stereotactic radiotherapy under cone beam CT image guidance with a six-degrees-of-freedom robotic couch and a mouthpiece-assisted mask system: a preliminary study.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Naoi, Y. Kunishima, N. Yamamoto, K. Yoda, K.
Description	Country affiliation: Japan Author Affiliation: Naoi Y ( 1 Department of Radiology, Self Defense Forces Central Hospital, Tokyo, Japan.)
Abstract	OBJECTIVE: A planning target volume (PTV) margin formula for hypofractionated intracranial stereotactic radiotherapy (SRT) has been proposed under cone beam CT (CBCT) image guidance with a six-degrees-of-freedom (6-DOF) robotic couch. METHODS: CBCT-based registration using a 6-DOF couch reportedly led to negligibly small systematic positioning errors, suggesting that each in-treatment positioning error during the treatment courses for the patients employing this combination was predominantly caused by a random gaussian process. Under this assumption, an anisotropic PTV margin for each axis was formulated based on a gaussian distribution model. 19 patients with intracranial lesions who underwent additional post-treatment CBCT were consecutively selected, to whom stereotactic hypofractionated radiotherapy was delivered by a linear accelerator equipped with a CBCT imager, a 6-DOF couch and a mouthpiece-assisted mask system. Time-averaged patient-positioning errors during treatment were estimated by comparing the post-treatment CBCT with the reference planning CT images. RESULTS: It was suggested that each histogram of the in-treatment positioning error in each axis would approach each single gaussian distribution with a mean of zero. The calculated PTV margins in the x, y and z directions were 0.97, 1.30 and 0.88 mm, respectively. CONCLUSION: The empirical isotropic PTV margin of 2 mm used in our facility for intracranial SRT was consistent with the margin calculated by the proposed gaussian model. ADVANCES IN KNOWLEDGE: We have proposed a PTV margin formula for hypofractionated intracranial SRT under CBCT image guidance with a 6-DOF robotic couch.
File Format	HTM / HTML
ISSN	00071277
DOI	10.1259/bjr.20140240
Journal	The British Journal of Radiology
Issue Number	1041
Volume Number	87
Language	English
Publisher	BIR Publications
Publisher Date	2014-09-01
Publisher Place	Great Britain (UK)
Access Restriction	Open
Subject Keyword	Robotic Surgical Procedures Patient Positioning Radiosurgery Radiotherapy Planning, Computer-assisted Instrumentation Equipment Design Imaging, Three-dimensional Cone-beam Computed Tomography Dose Fractionation Surgery, Computer-assisted Discipline Radiology
Content Type	Text
Resource Type	Article

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