NDLI: Two new isoaurones derivatives from Callistephus chinensis flower.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Zhang, Xiao-shu Cao, Jia-qing Shi, Guo-hui Liu, Zhen-ting Liu, Jing-xin Zhao, Yu-qing
Spatial Coverage	China
Description	Author Affiliation: Zhang XS ( a School of Traditional Chinese Medicine, Shenyang Pharmaceutical University , Shenyang 110016 , People's Republic of China.); Cao JQ ( b Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang PharmaceuticalUniversity , Shenyang 110016 , People's Republic of China.); Shi GH ( a School of Traditional Chinese Medicine, Shenyang Pharmaceutical University , Shenyang 110016 , People's Republic of China.); Liu ZT ( b Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang PharmaceuticalUniversity , Shenyang 110016 , People's Republic of China.); Liu JX ( c School of Pharmacy, Jiangxi University of Traditional Chinese Medicine , Nanchang 330004 , People's Republic of China.); Zhao YQ ( d Chifeng MinYi Natural Anthocyanins Company Limited , Inner Mongolia Autonomous Region 024000 , People's Republic of China.)
Abstract	Two new isoaurones derivatives were obtained from Callistephus chinensis flower. Their structures were elucidated on the basis of extensive spectroscopic analyses. Both of the new compounds were evaluated cytotoxic activity. Phytochemical investigation of Callistephus chinensis flower led to the isolation of two new isoaurones derivatives (Z)-4',4,10-trihydroxy-siamaurone (1) and (E)-4',4,10-trihydroxy-siamaurone (2). The structures of these new compounds were identified by the interpretation of spectroscopic data (mainly 1D and 2D NMR) and by comparison with data reported in the literature. Both of the new compounds were evaluated for their cytotoxicity.
File Format	HTM / HTML
ISSN	14786419
Issue Number	3
Volume Number	30
e-ISSN	14786427
Journal	Natural Product Research
Language	English
Publisher	Taylor & Francis
Publisher Date	2016-01-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Research Support, Non-u.s. Gov't Discipline Natural products Magnetic Resonance Spectroscopy Humans Isolation & Purification Discipline Natural Products Pharmacology Flowers Benzofurans Drug Effects Journal Article Chemistry China Asteraceae Cell Line, Tumor Inhibitory Concentration 50 Molecular Structure Methods Drug Screening Assays, Antitumor
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Plant Science Analytical Chemistry Biochemistry

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