| Content Provider |
World Health Organization (WHO)-Global Index Medicus |
| Author |
Zhou, Yu Yang, Peng-Fei Li, Qiang Zhao, Rui Fang, Yi-Bin Xu, Yi Hong, Bo Zhao, Wen-Yuan Huang, Qing-Hai Liu, Jian-Min |
| Description |
Country affiliation: China Author Affiliation: Zhou Y ( Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.); Yang PF ( Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.); Li Q ( Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.); Zhao R ( Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.); Fang YB ( Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.); Xu Y ( Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.); Hong B ( Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.); Zhao WY ( Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.); Huang QH ( Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.); Liu JM ( Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China. Electronic address: liu118@vip.163.com.) |
| Abstract |
BACKGROUND: To evaluate the safety and effectiveness of stent placement for ruptured or unruptured middle cerebral artery (MCA) aneurysms in a larger number. METHODS: Between October 2003 and December 2012, data for 70 patients with 72 complex MCA aneurysms treated with stents at our institution were retrospectively collected and analyzed. RESULTS: Eighty-five stents were successfully deployed in this series. However, failure of followed coiling was encountered in 2 (2.8%) tiny aneurysms of them. Of the 63 aneurysms treated with stent-assisted coiling, complete occlusion was achieved in 22 (34.9%), neck remnant in 15 (23.8%), and residual sac in 26 (36.5%). Of the 9 aneurysms treated with stent alone, the results were contrast stasis in 3 aneurysms and no change in 6. Procedure-related complications occurred in 9 (12.5%) procedures, including 7 of 27 (25.9%) with ruptured aneurysms and 2 of 45 (4.4%) with unruptured aneurysms, which resulted in 1 death and 5 disabilities. Univariate and multivariate analyses show that ruptured aneurysm is an independent factor for the outcome of these patients (odds ratio, 7.35; 95% confidence interval, 1.35-40.0). Angiographic follow-up results (mean, 10.5±8.8 months) showed that 72.1% (44 of 61) were completely occluded, 4.9% (3 of 61) recurred, and others were stable or had improved. Intrastent stenosis was observed in 1 (1.6%) patient, which was managed conservatively. During a clinical follow-up period ranging from 7 to 113 months (mean, 33.0±22.4 months), 1 disabled patient died from severe pneumonia, whereas the clinical status of the others had improved or was stable. Procedure-related morbidity/mortality during the follow-up for the ruptured and unruptured groups were 3.7%/3.7% and 0/0, respectively. CONCLUSIONS: Our study shows that stent placement for the treatment of certain wide-neck MCA aneurysms is feasible, safe, and effective. However, stent placement for acutely ruptured MCA aneurysms harbors a much higher complication rate. |
| File Format |
HTM / HTML |
| ISSN |
10523057 |
| Issue Number |
6 |
| Volume Number |
23 |
| e-ISSN |
15328511 |
| Journal |
Journal of Stroke and Cerebrovascular Diseases |
| Language |
English |
| Publisher |
Elsevier |
| Publisher Date |
2014-07-01 |
| Publisher Place |
United States |
| Access Restriction |
One Nation One Subscription (ONOS) |
| Subject Keyword |
Anticoagulants Research Support, Non-u.s. Gov't Aspirin Humans Middle Aged Drug Therapy Intracranial Aneurysm Male Treatment Outcome Therapeutic Use Journal Article Aneurysm, Ruptured Ticlopidine Cerebral Angiography Discipline Cardiology Surgery Treatment Failure Platelet Aggregation Inhibitors Adult Female Aged Retrospective Studies Stents Analogs & Derivatives |
| Content Type |
Text |
| Resource Type |
Article |
| Subject |
Rehabilitation Neurology (clinical) Surgery Cardiology and Cardiovascular Medicine |
