NDLI: Comparing the effects of tetrabromobisphenol-A, bisphenol A, and their potential replacement alternatives, TBBPA-bis(2,3-dibromopropyl ether) and bisphenol S, on cell viability and messenger ribonucleic acid expression in chicken embryonic hepatocytes.

Please wait, while we are loading the content...

GEMAS: Prediction of solid-solution partitioning coefficients $(K_{d})$ for cationic metals in soils using mid-infrared diffuse reflectance spectroscopy

Effects of benzo[a]pyrene on growth, the antioxidant system, and DNA damage in earthworms (Eisenia fetida) in 2 different soil types under laboratory conditions.

Environmental biodegradability of [¹4C] single-walled carbon nanotubes by Trametes versicolor and natural microbial cultures found in New Bedford Harbor sediment and aerated wastewater treatment plant sludge.

Metformin exposure at environmentally relevant concentrations causes potential endocrine disruption in adult male fish.

Bioaccumulation of metals and metalloids in medicinal plant Ipomoea pes-caprae from areas impacted by tsunami.

Environmental fate of emamectin benzoate after tree micro injection of horse chestnut trees.

Environmental contaminants and chromosomal damage associated with beak deformities in a resident North American passerine.

Fate and effects of clothianidin in fields using conservation practices.

Hg-contaminated terrestrial spiders pose a potential risk to songbirds at Caddo Lake (Texas/Louisiana, USA).

Sources of endocrine-disrupting compounds in North Carolina waterways: a geographic information systems approach.

No observable effect of a glyphosate-based herbicide on two top predators of temporal water bodies.

Automated method for determination of dissolved organic carbon-water distribution constants of structurally diverse pollutants using pre-equilibrium solid-phase microextraction.

Silver nanoparticle toxicity to Atlantic killifish (Fundulus heteroclitus) and Caenorhabditis elegans: A comparison of mesocosm, microcosm, and conventional laboratory studies

Effects of climate change on the toxicity of soils polluted by metal mine wastes to Enchytraeus crypticus.

A mixture of environmental organic contaminants in lake sediments affects hatching from Daphnia resting eggs.

Cross-basin comparison of mercury bioaccumulation in Lake Huron lake trout emphasizes ecological characteristics.

Interaction between nickel and cobalt toxicity in Enchytraeus crypticus is due to competitive uptake.

Biotransformation of dichlorodiphenyltrichloroethane in the benthic polychaete, Nereis succinea: quantitative estimation by analyzing the partitioning of chemicals between gut fluid and lipid.

Comparing the effects of tetrabromobisphenol-A, bisphenol A, and their potential replacement alternatives, TBBPA-bis(2,3-dibromopropyl ether) and bisphenol S, on cell viability and messenger ribonucleic acid expression in chicken embryonic hepatocytes.

Effects of progesterone and norethindrone on female fathead minnow (Pimephales promelas) steroidogenesis.

European Chemicals Agency dossier submissions as an experimental data source: refinement of a fish toxicity model for predicting acute LC50 values.

A review of mercury concentrations in freshwater fishes of Africa: patterns and predictors.

Inter- and intraspecies chemical sensitivity: a case study using 2,4-dinitroanisole.

GEMAS: prediction of solid-solution phase partitioning coefficients (Kd) for oxoanions and boric acid in soils using mid-infrared diffuse reflectance spectroscopy.

Cardiac toxicity by sublethal 2,3,7,8-tetrachlorodibenzo-p-dioxin correlates with its anti-proliferation effect on cardiomyocytes in zebrafish embryos.

Inhibition effect of $Na^{+}$ and $Ca^{2+}$ on the bioaccumulation of perfluoroalkyl substances by Daphnia magna in the presence of protein

Zebra mussels (Dreissena polymorpha) as a biomonitor of trace elements along the southern shoreline of Lake Michigan.

Year: 2015 Volume: 34 Issue: 1

Year: 2014 Volume: 33

Year: 2013 Volume: 32

Year: 2012 Volume: 31

Year: 2011 Volume: 30

Year: 2010 Volume: 29

Year: 2009 Volume: 28

Year: 2008 Volume: 27

Year: 2007 Volume: 26

Year: 2006 Volume: 25

Year: 2004 Volume: 23

Comparing the effects of tetrabromobisphenol-A, bisphenol A, and their potential replacement alternatives, TBBPA-bis(2,3-dibromopropyl ether) and bisphenol S, on cell viability and messenger ribonucleic acid expression in chicken embryonic hepatocytes.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Ma, Melissa Crump, Doug Farmahin, Reza Kennedy, Sean W.
Description	Country affiliation: Canada Author Affiliation: Ma M ( National Wildlife Research Centre, Environment Canada, Ottawa, Ontario, Canada.)
Abstract	A market for alternative brominated flame retardants (BFRs) has emerged recently due to the phase out of persistent and inherently toxic BFRs. Several of these replacement compounds have been detected in environmental matrices, including wild birds. A chicken embryonic hepatocyte (CEH) assay was utilized to assess the effects of the BFR, tetrabromobisphenol-A (TBBPA), and its replacement alternative, tetrabromobisphenol A bis(2,3-dibromopropyl ether [TBBPA-DBPE]) on cell viability and messenger ribonucleic acid (mRNA) expression. Bisphenol A (BPA) and 1 of its replacement alternatives, bisphenol S (BPS), were also screened for effects. Both TBBPA and BPA decreased CEH viability with calculated median lethal concentration (LC50) values of 40.6 µM and 61.7 µM, respectively. However, the replacement alternatives, TBBPA-DBPE and BPS, did not affect cell viability (up to 300 µM). Effects on mRNA expression were determined using an Avian ToxChip polymerse chain reaction (PCR) array and a real-time (RT)-PCR assay for the estrogen-responsive genes, apolipoproteinII (ApoII) and vitellogenin (Vtg). A luciferase reporter gene assay was used to assess dioxin-like effects. Tetrabromobisphenol-A altered mRNA levels of 4 genes from multiple toxicity pathways and increased luciferase activity in the luciferase reporter gene assay, whereas its alternative, TBBPA-DBPE, only altered 1 gene on the array, Cyp1a4, and increased luciferase activity. At 300 µM, a concentration that decreased cell viability for TBBPA and BPA, the BPA replacement, BPS, altered the greatest number of transcripts, including both ApoII and Vtg. Bisphenol A exposure did not alter any genes on the array but did up-regulate Vtg at 10 µM. Characterization of the potential toxicological and molecular-level effects of these compounds will ideally be useful to chemical regulators tasked with assessing the risk of new and existing chemicals.
File Format	HTM / HTML
ISSN	07307268
Issue Number	2
Volume Number	34
e-ISSN	15528618
Journal	Environmental Toxicology and Chemistry
Language	English
Publisher	Wiley
Publisher Date	2015-02-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Research Support, Non-u.s. Gov't Comparative Study Toxicity Discipline Environmental Health Cytology Apolipoprotein A-ii Discipline Toxicology Journal Article Polymerase Chain Reaction Discipline Chemistry Polybrominated Biphenyls Genetics Sulfones Benzhydryl Compounds Bromobenzenes Cell Survival Rna, Messenger Metabolism Drug Effects Chick Embryo Chemistry Animals Hepatocytes Phenols Vitellogenins Toxicity Tests
Content Type	Text
Resource Type	Article
Subject	Environmental Chemistry Health, Toxicology and Mutagenesis

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Bisphenol A and its analogs: Do their metabolites have endocrine activity?

Biotransformation of the flame retardant tetrabromobisphenol-A (TBBPA) by freshwater microalgae.

Toxicity assessment and vitellogenin expression in zebrafish (Danio rerio) embryos and larvae acutely exposed to bisphenol A, endosulfan, heptachlor, methoxychlor and tetrabromobisphenol A.

Occurrence and profiles of bisphenol analogues in municipal sewage sludge in China.

Tetrabromobisphenol A (TBBPA): Possible modes of action of toxicity and carcinogenicity in rodents.

Evaluation of the toxic effects of brominated compounds (BDE-47, 99, 209, TBBPA) and bisphenol A (BPA) using a zebrafish liver cell line, ZFL.

Characteristics, sources, and transport of tetrabromobisphenol A and bisphenol A in soils from a typical e-waste recycling area in South China.

Embryonic exposure to tetrabromobisphenol A and its metabolites, bisphenol A and tetrabromobisphenol A dimethyl ether disrupts normal zebrafish (Danio rerio) development and matrix metalloproteinase expression.

Adult fathead minnow, Pimephales promelas, partial life-cycle reproductive and gonadal histopathology study with bisphenol A.

Comparing the effects of tetrabromobisphenol-A, bisphenol A, and their potential replacement alternatives, TBBPA-bis(2,3-dibromopropyl ether) and bisphenol S, on cell viability and messenger ribonucleic acid expression in chicken embryonic hepatocytes.

Similar Documents

Bisphenol A and its analogs: Do their metabolites have endocrine activity?

Biotransformation of the flame retardant tetrabromobisphenol-A (TBBPA) by freshwater microalgae.

Toxicity assessment and vitellogenin expression in zebrafish (Danio rerio) embryos and larvae acutely exposed to bisphenol A, endosulfan, heptachlor, methoxychlor and tetrabromobisphenol A.

Occurrence and profiles of bisphenol analogues in municipal sewage sludge in China.

Tetrabromobisphenol A (TBBPA): Possible modes of action of toxicity and carcinogenicity in rodents.

Evaluation of the toxic effects of brominated compounds (BDE-47, 99, 209, TBBPA) and bisphenol A (BPA) using a zebrafish liver cell line, ZFL.

Characteristics, sources, and transport of tetrabromobisphenol A and bisphenol A in soils from a typical e-waste recycling area in South China.

Embryonic exposure to tetrabromobisphenol A and its metabolites, bisphenol A and tetrabromobisphenol A dimethyl ether disrupts normal zebrafish (Danio rerio) development and matrix metalloproteinase expression.

Adult fathead minnow, Pimephales promelas, partial life-cycle reproductive and gonadal histopathology study with bisphenol A.

Comparing the effects of tetrabromobisphenol-A, bisphenol A, and their potential replacement alternatives, TBBPA-bis(2,3-dibromopropyl ether) and bisphenol S, on cell viability and messenger ribonucleic acid expression in chicken embryonic hepatocytes.