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Year: 2017 Volume: 95

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Dimensional reduction in Bose-Einstein condensed clouds of atoms confined in tight potentials of any geometry and any interaction strength.

Large deviations in Taylor dispersion.

Long-range interacting systems in the unconstrained ensemble.

Dense plasma heating by crossing relativistic electron beams.

Diffusion of a Rouse chain in porous media: A mode-coupling-theory study

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Tracer counterpermeation analysis of diffusivity in finite-length nanopores with and without single-file dynamics

Bistable director alignments of nematic liquid crystals confined in frustrated substrates.

Quantum Kramers model: Corrections to the linear response theory for continuous bath spectrum

Microfield dynamics in dense hydrogen plasmas with high-Z impurities.

Robustness and fragility in coupled oscillator networks under targeted attacks.

Dynamic model for kinesin-mediated long-range transport and its local traffic jam caused by tau proteins.

High-efficiency $ γ $ -ray flash generation via multiple-laser scattering in ponderomotive potential well

Ising spin glasses in dimension five.

Upper and lower critical decay exponents of Ising ferromagnets with long-range interaction

Adsorption-induced shape transitions in bistable nanopores with atomically thin walls.

One-loop diagrams in the random Euclidean matching problem.

Effects of flexoelectricity and weak anchoring on a Freedericksz transition cell.

Issues associated with Galilean invariance on a moving solid boundary in the lattice Boltzmann method.

Self-similar asymptotic optical beams in semiconductor waveguides doped with quantum dots.

Persistent homology analysis of craze formation.

Heterogeneous out-of-equilibrium nonlinear $ q $ -voter model with zealotry

Reynolds-number dependence of the dimensionless dissipation rate in homogeneous magnetohydrodynamic turbulence

Richtmyer-Meshkov instability of a flat interface subjected to a rippled shock wave

Stochastic Liouville equation for particles driven by dichotomous environmental noise.

Impact dynamics of particle-coated droplets

Reynolds number effects on the single-mode Richtmyer-Meshkov instability.

Universal time-dependent dispersion properties for diffusion in a one-dimensional critically tilted potential

Synchronization and long-time memory in neural networks with inhibitory hubs and synaptic plasticity

Fundamental difference between superblockers and superspreaders in networks.

Scaling features of the tribology of polymer brushes of increasing grafting density around the mushroom-to-brush transition

Effect of similarity between patterns in associative memory.

Phase reduction theory for hybrid nonlinear oscillators.

Collective colloid diffusion under soft two-dimensional confinement

First-order transition in a percolation model with nucleation and preferential growth

Mechanical stability of particle-stabilized droplets under micropipette aspiration.

Density of states from mode expansion of the self-dynamic structure factor of a liquid metal.

Particles with nonlinear electric response: Suppressing van der Waals forces by an external field.

Propelling and spinning of microsheets in nematic liquid crystals driven by ac electric field.

Effects of gas interparticle interaction on dissipative wake-mediated forces.

Lévy flights in the presence of a point sink of finite strength.

Effects of burstiness on the air transportation system.

Higher-order effects on the properties of the optical compact bright pulse: Collective variable approach.

Solar potential scaling and the urban road network topology.

Noise-enhanced chaos in a weakly coupled GaAs/(Al,Ga)As superlattice

Signatures of bifurcation on quantum correlations: Case of the quantum kicked top.

Interaction, coalescence, and collapse of localized patterns in a quasi-one-dimensional system of interacting particles.

Oscillatory pulses and wave trains in a bistable reaction-diffusion system with cross diffusion.

Detectability thresholds of general modular graphs.

Critical behavior of the spin-1 and spin-3/2 Baxter-Wu model in a crystal field.

Coupling strength versus coupling impact in nonidentical bidirectionally coupled dynamics.

Simple diffusion hopping model with convection.

Conserved nonlocal dynamics and critical behavior of uranium ferromagnetic superconductors

Ferromagnetic model on the Apollonian packing

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Evolutionary games with coordination and self-dependent interactions.

Radiative transfer dynamo effect.

Random walk in degree space and the time-dependent Watts-Strogatz model.

Traffic congestion and the lifetime of networks with moving nodes.

Emergent pattern formation in an interstitial biofilm.

Network susceptibilities: Theory and applications.

Radiative heat transfer as a Landauer-Büttiker problem.

Clustering determines the dynamics of complex contagions in multiplex networks.

Stochastic boundary approaches to many-particle systems coupled to a particle reservoir.

Stable parity-time-symmetric nonlinear modes and excitations in a derivative nonlinear Schrödinger equation.

Effects of hydrodynamic interactions on rectified transport of self-propelled particles.

Analysis of the classical phase space and energy transfer for two rotating dipoles with and without external electric field.

Reconstructing links in directed networks from noisy dynamics.

Prediction of the moments in advection-diffusion lattice Boltzmann method. I. Truncation dispersion, skewness, and kurtosis

Inferring hidden states in Langevin dynamics on large networks: Average case performance.

Peak-height formula for higher-order breathers of the nonlinear Schrödinger equation on nonuniform backgrounds.

Criticality of colloids with three distinct interaction patches: As simple as $ A , B , C $ ?

Power-law statistics and universal scaling in the absence of criticality.

Solving the spin-2 Gross-Pitaevskii equation using exact nonlinear dynamics and symplectic composition.

Kinetics of motility-induced phase separation and swim pressure.

Statistical model of a flexible inextensible polymer chain: The effect of kinetic energy.

Network clustering and community detection using modulus of families of loops.

Nonequilibrium Markov state modeling of the globule-stretch transition.

Effect of curvature on cholesteric liquid crystals in toroidal geometries.

Geometry and design of origami bellows with tunable response.

Band instability in near-critical fluids subjected to vibration under weightlessness

Physics of negative absolute temperatures.

Nonvariational mechanism of front propagation: Theory and experiments.

Optimizing synchronization stability of the Kuramoto model in complex networks and power grids.

Collective dynamics of time-delay-coupled phase oscillators in a frustrated geometry.

Phase transition in the majority-vote model on the Archimedean lattices.

Impact of lipid rafts on the T-cell-receptor and peptide-major-histocompatibility-complex interactions under different measurement conditions.

Driven tracers in narrow channels.

Applicability of the Fokker-Planck equation to the description of diffusion effects on nucleation.

Experimental observation of oscillatory cellular patterns in three-dimensional directional solidification

Supersymmetric spin chains with nonmonotonic dispersion relation: Criticality and entanglement entropy.

Measurements of the stabilities of isolated retinal chromophores.

Exactly solvable model for cluster-size distribution in a closed system

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Translational diffusion across a free-standing smectic film above the bulk smectic- $ A $ –isotropic transition temperature

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Stochastically gated local and occupation times of a Brownian particle.

Markovian quantum master equation beyond adiabatic regime

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Local equilibria and state transfer of charged classical particles on a helix in an electric field.

Minimal model for anomalous diffusion

Neutral aggregation in finite-length genotype space.

Friction factor for aerosol fractal aggregates over the entire Knudsen range.

Jump transition observed in translocation time for ideal poly-X proteinogenic chains as a result of competing folding and anchoraging contributions.

Thermostability analysis of line-tension-associated nucleation at a gas-liquid interface.

Experimental investigation of interfacial energy transport in an evaporating sessile droplet for evaporative cooling applications.

Terahertz generation from laser-driven ultrafast current propagation along a wire target

Mixing with applications to inertial-confinement-fusion implosions.

Einstein-Podolsky-Rosen paradox implies a minimum achievable temperature.

Hydrodynamic mobility of a solid particle near a spherical elastic membrane: Axisymmetric motion.

Thermodynamic framework for the ground state of a simple quantum system

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Interaction force between two finite-size charged particles in weakly ionized plasma.

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Thermodynamics and superradiant phase transitions in a three-level Dicke model.

Exact results for power spectrum and susceptibility of a leaky integrate-and-fire neuron with two-state noise.

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Search in patchy media: Exploitation-exploration tradeoff

Nonorthogonal central-moments-based lattice Boltzmann scheme in three dimensions.

Effect of friction on dense suspension flows of hard particles

Mechanisms of jamming in the Nagel-Schreckenberg model for traffic flow

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Merits and qualms of work fluctuations in classical fluctuation theorems

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Smallest chimera states.

Charge segregation in weakly ionized microgels.

Local average height distribution of fluctuating interfaces.

Geometric somersaults of a polymer chain through cyclic twisting motions

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Pulse-noise approach for classical spin systems.

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Influence of trust in the spreading of information.

Conducting-insulating transition in adiabatic memristive networks.

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Thermal effects in dislocation theory. II. Shear banding.

Mori-Zwanzig theory for dissipative forces in coarse-grained dynamics in the Markov limit.

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Critical phenomena on $ k $ -booklets

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Acoustic streaming in two-dimensional freely suspended smectic liquid crystal films.

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Hybrid lattice Boltzmann method on overlapping grids.

Analysis of thermodiffusive cellular instabilities in continuum combustion fronts.

Non-Markovian linear response theory for quantum open systems and its applications.

Non-Hermitian surface hopping.

Key-lock colloids in a nematic liquid crystal

Exotic phase transitions of k-cores in clustered networks.

Next-to-leading-order corrections to capacity for a nondispersive nonlinear optical fiber channel in the intermediate power region.

Bifurcation induced by the aspect ratio in a turbulent von Kármán swirling flow.

Impact of diffusion on surface clustering in random hydrodynamic flows.

Self-tuning bistable parametric feedback oscillator: Near-optimal amplitude maximization without model information.

Transverse vibration of nematic elastomer Timoshenko beams.

Escape rate of active particles in the effective equilibrium approach.

Aging underdamped scaled Brownian motion: Ensemble- and time-averaged particle displacements, nonergodicity, and the failure of the overdamping approximation.

Pair approximation for the q-voter model with independence on complex networks.

Subtle escaping modes and subset of patterns from a nonhyperbolic chaotic attractor.

Effective potential theory for diffusion in binary ionic mixtures.

Coherent libration to coherent rotational dynamics via chimeralike states and clustering in a Josephson junction array.

Stimulated Raman scattering in the relativistic regime in near-critical plasmas

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Geometrical model for martensitic phase transitions: Understanding criticality and weak universality during microstructure growth.

Dynamic shear jamming in dense granular suspensions under extension.

Nonequilibrium temperature measurement in a thermal conduction process.

Inertia and universality of avalanche statistics: The case of slowly deformed amorphous solids.

Percolation of binary disk systems: Modeling and theory.

Feynman-Kac formula for stochastic hybrid systems.

Extension of discrete tribocharging models to continuous size distributions.

Universality and asymptotic scaling in drilling percolation.

Coarsening and persistence in a one-dimensional system of orienting arrowheads: Domain-wall kinetics with $ A + B → 0 $

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Sign changes as a universal concept in first-passage-time calculations.

Birefringence in the vicinity of the smectic-A to smectic-C phase transition: Crossover from XY critical to tricritical behavior.

Separation of cyclic and starlike hierarchical dominance in evolutionary matrix games.

Onset of shear thinning in glassy liquids: Shear-induced small reduction of effective density

Structure-diffusion relationship of polymer membranes with different texture.

Solving the two-dimensional Fokker-Planck equation for strongly correlated neurons.

Self-diffusion in two-dimensional binary colloidal hard-sphere fluids.

Validity of the no-pumping theorem in systems with finite-range interactions between particles.

Correlation-powered information engines and the thermodynamics of self-correction.

Orientational action of edge dislocations on the director field in antiferroelectric smectic- $ C _{ A }^{ * } $ films

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Dynamic model for kinesin-mediated long-range transport and its local traffic jam caused by tau proteins.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Nam, Woochul Epureanu, Bogdan I.
Description	Country affiliation: United States Author Affiliation: Nam W ( University of Michigan, Ann Arbor, Michigan 48105, USA.); Epureanu BI ( University of Michigan, Ann Arbor, Michigan 48105, USA.)
Abstract	In neurons, several intracellular cargoes are transported by motor proteins (kinesins) which walk on microtubules (MTs). However, kinesins can possibly unbind from the MTs before they reach their destinations. The unbound kinesins randomly diffuse in neurons until they bind to MTs. Then, they walk again along the MTs to continue their tasks. Kinesins repeat this cycle of motion until they transport their cargoes to the destinations. However, most previous models mainly focused on the motion of kinesins when they walk on MTs. Thus, a new model is required to encompass the various types of kinesin motion. We developed a comprehensive model and studied the long-range axonal transport of neurons using the model. To enhance reliability of the model, it was constructed based on multiphysics on kinesin motion (i.e., chemical kinetics, diffusion, fluid dynamics, nonlinear dynamics, and stochastic characteristics). Also, parameter values for kinesin motions are carefully obtained by comparing the model predictions and several experimental observations. The axonal transport can be degraded when a large number of binding sites on MTs are blocked by excessive tau proteins. By considering the interference between walking kinesins and tau molecules on MTs, effects of tau proteins on the axonal transport are studied. One of the meaningful predictions obtained from the model is that the velocity is not an effective metric to estimate the degradation of the transport because the decrease in velocity is not noticeable when the concentration of tau protein is not high. However, our model shows that the transport locally changes near tau molecules on MTs even when the change in the velocity is not significant. Thus, a statistical method is proposed to detect this local change effectively. The advantage of this method is that a value obtained from this method is highly sensitive to the concentration of tau protein. Another benefit of this method is that this highly sensitive value can be acquired with relatively low precision and low temporal resolution considering the time scale and length scale of the kinesin motion. This method can be used to estimate the condition of the axonal transport system.
File Format	HTM / HTML
ISSN	24700045
e-ISSN	24700053
Journal	Physical Review E
Issue Number	1-1
Volume Number	95
Language	English
Publisher	American Physical Society
Publisher Date	2017-01-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Statistical and Nonlinear Physics many-body systems Condensed Matter Physics
Content Type	Text
Resource Type	Article
Subject	Statistics and Probability Statistical and Nonlinear Physics Condensed Matter Physics

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