NDLI: Synthesis and photobactericidal properties of a neutral porphyrin grafted onto lignocellulosic fibers.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Nzambe Ta keki, Jean Kerim Ouk, Tan-Sothéa Zerrouki, Rachida Faugeras, Pierre-Antoine Sol, Vincent Brouillette, François
Description	Country affiliation: France Author Affiliation: Nzambe Ta keki JK ( Laboratoire de chimie des substances naturelles, Université de Limoges, 123 avenue Albert Thomas, 87060 Limoges, France.); Ouk TS ( Laboratoire de chimie des substances naturelles, Université de Limoges, 123 avenue Albert Thomas, 87060 Limoges, France.); Zerrouki R ( Laboratoire de chimie des substances naturelles, Université de Limoges, 123 avenue Albert Thomas, 87060 Limoges, France); Faugeras PA ( Laboratoire de chimie des substances naturelles, Université de Limoges, 123 avenue Albert Thomas, 87060 Limoges, France.); Sol V ( Laboratoire de chimie des substances naturelles, Université de Limoges, 123 avenue Albert Thomas, 87060 Limoges, France.); Brouillette F ( Centre de Recherche sur les Matériaux Lignocellulosiques, Université du Québec à Trois-Rivières, 3351 boul. des Forges, C.P. 500, Trois-Rivières, QC G9A 5H7, Canada.)
Abstract	Photodynamic antimicrobial chemotherapy (PACT), as one of the promising alternative antimicrobial treatment, has received great attention in recent years. In this work, a new antimicrobial material has been elaborated by grafting a neutral porphyrin, the metallated 5-(4-azidophenyl)-10,15,20-triphenylporphyrin, onto lignocellulosic fibers by using the Copper (I)-Catalyzed Alkyne-Azide 1,3-dipolar Cycloaddition (CuAAC) reaction. The cross-linked porphyrin-Kraft pulp material was characterized by infrared and by XPS spectroscopy analyses, which proved the covalent linkage between the porphyrin and propargylated Kraft pulp fibers. The antimicrobial activity of this material was tested under visible light irradiation with a low light dose (9.5 J/cm(2)) against Staphylococcus aureus and Pseudomonas aeruginosa. The two bacterial strains deposited on the resulting photosensitizing Kraft pulp are efficiently killed after illumination. Such materials could find applications in industrial, household and medical environments as an alternative to overcome the widespread microbial multiresistance to classical treatments.
File Format	HTM / HTML
ISSN	09284931
Journal	Materials Science and Engineering: C
Volume Number	62
e-ISSN	18730191
Language	English
Publisher	Elsevier
Publisher Date	2016-05-01
Publisher Place	Netherlands
Access Restriction	Subscribed
Content Type	Text
Resource Type	Article
Subject	Mechanics of Materials Biomaterials Condensed Matter Physics Bioengineering Mechanical Engineering

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