NDLI: Antibody-coupled hydroxyapatite nanoparticles as efficient tools for labeling intracellular proteins.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Vázquez-Hernández, Fabiola Mendoza-Acevedo, Salvador Mendoza-Barrera, Claudia Oliva Mendoza-Álvarez, Julio Luna-Arias, Juan Pedro
Description	Author Affiliation: Vázquez-Hernández F ( Programa de Doctorado de Nanociencias y Nanotecnología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Av. IPN 2508, Col. San Pedro Zacatenco, C.P. 07360 Ciudad de México, Mexico. Electronic address: fvazquez_84@yahoo.com.mx.); Mendoza-Acevedo S ( Centro de Investigación en Computación del Instituto Politécnico Nacional (CIC-IPN), Av. Juan de Dios Bátiz, Esq. Miguel Othón de Mendizábal, Col. Nueva Industrial Vallejo, C.P. 07738 Ciudad de México, Mexico. Electronic address: smendozaa10@gmail.com.); Mendoza-Barrera CO ( Laboratorio de Nanobiotecnología, Centro de Investigación en Micro y Nanotecnología (MICRONA), Universidad Veracruzana, C.P. 94294 Boca del Río, Veracruz, Mexico. Electronic address: cmendoza_barrera@hotmail.com.); Mendoza-Álvarez J ( Departamento de Física, Cinvestav-IPN, Av. IPN 2508, Col. San Pedro Zacatenco, C.P. 07360 Ciudad de México, Mexico. Electronic address: juliogma1@gmail.com.); Luna-Arias JP ( Programa de Doctorado de Nanociencias y Nanotecnología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Av. IPN 2508, Col. San Pedro Zacatenco, C.P. 07360 Ciudad de México, Mexico)
Abstract	Smart biomaterials for active targeting are a novel way for biosensing, gene and drug delivery, and bioimaging. The functional additives are chosen according to the material carrier characteristics, i.e. the functional mercapto acids of different lengths. In order to identify the target tissue, cell, organ or molecule, the biomaterial must be equipped with a recognizing molecule on its surface. In most cases, semiconductor o metal materials are employed in bioimaging and biosensing applications; in gene and drug delivery area, it is useful to employ porous nanoparticles as carriers. Hydroxyapatite nanoparticles have been proved efficiently in drug delivery. In this work we established a new protocol to obtain smart hydroxyapatite nanoparticles with 3-mercaptopropionic acid and anti-Actin molecules in order to localize actin molecules in cells.
File Format	HTM / HTML
ISSN	09284931
Journal	Materials Science and Engineering: C
Volume Number	71
e-ISSN	18730191
Language	English
Publisher	Elsevier
Publisher Date	2017-02-01
Publisher Place	Netherlands
Access Restriction	Subscribed
Content Type	Text
Resource Type	Article
Subject	Mechanics of Materials Biomaterials Condensed Matter Physics Bioengineering Mechanical Engineering

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