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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Leverstein-van Hall, Maurine A. Hopmans, Titia E. M. Van Der Sprenkel, Jan Willem Berkelbach Blok, Hetty E. M. Van Der Mark, Wil A. M. A. Hanlo, Patrick W. Bonten, Marc J. M. |
| Description | Country affiliation: Netherlands Author Affiliation: Leverstein-van Hall MA ( Department of Microbiology, Infectious Diseases and Inflammation, and Hospital Hygiene and Infection Prevention, Utrecht, The Netherlands. M.LeversteinvHall@umcutrecht.nl) |
| Abstract | OBJECT: An important complication of external CSF drainage is bacterial meningitis or ventriculitis, resulting in increased morbidity, mortality, and health care costs. In 2003, a high rate (37%) of probable drain-related infections was identified at the authors' hospital. A multidisciplinary working group was installed to reduce this incidence to < 10% within 1.5 years. METHODS: An intervention strategy based on 5 pillars (increased awareness, focused standard operating procedures, a diagnostic and therapeutic algorithm, timely administration of prophylaxis, and improvement of the drainage system) was designed and implemented from 2004 to 2006. During this period all patients with external CSF drainage were prospectively monitored. RESULTS: Between 2004 and 2006, there were 467 patients in whom 579 drains (external ventricular and external lumbar) had been placed. The overall incidence of drain-related infections was 16.2% in 2004, 8.9% in 2005, and 11.3% in 2006. For external lumbar drains the number of infections per 100 drain days was 2.4 in 2004, 0.6 in 2005, and 0.8 in 2006. For external ventricular drains these rates were 1.7, 1.0, and 1.2, respectively. Meanwhile, the causative noncutaneous microorganisms, indicative for systemic-contamination during manipulation, decreased. By retrospective analysis, the proportion of patients with a probable drain-related infection decreased from 37% in 2003 to 9% in 2005 and 2006. CONCLUSIONS: The authors' multidisciplinary approach in which different preventive measures were combined was associated with a significant reduction in the incidence of drain-related secondary meningitis, and thus provides an important improvement of patient safety. |
| File Format | HTM / HTML |
| ISSN | 00223085 |
| e-ISSN | 19330693 |
| Journal | Journal of Neurosurgery |
| Issue Number | 2 |
| Volume Number | 112 |
| Language | English |
| Publisher | American Association of Neurological Surgeons |
| Publisher Date | 2010-02-01 |
| Publisher Place | United States |
| Access Restriction | Open |
| Subject Keyword | Discipline Neurosurgery Central Nervous System Bacterial Infections Prevention & Control Cerebrospinal Fluid Drainage Adverse Effects Meningitis, Bacterial Adolescent Epidemiology Etiology Child, Preschool Infant Practice Guidelines As Topic Retrospective Studies |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neurology (clinical) Surgery |
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