NDLI: Incidence and mortality of bullous pemphigoid in France.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Joly, Pascal Baricault, Sophie Sparsa, Agnès Bernard, Philippe Bédane, Christophe Duvert-Lehembre, Sophie Courville, Philippe Bravard, Pierre Rémond, Brigitte Doffoel-Hantz, Valérie Bénichou, Jacques
Spatial Coverage	France
Description	Country affiliation: France Author Affiliation: Joly P ( Department of Dermatology, INSERM U905, Rouen University Hospital, University of Rouen, Rouen, France. Pascal.Joly@chu-rouen.fr)
Abstract	A major increase in the incidence of BP has been recently reported in the United Kingdom. In addition, there are some controversies about the over-mortality of BP patients. The primary objective was to reevaluate the incidence of BP in France as compared with that we estimated 15 years ago. The secondary objective was to assess mortality of BP patients. BP incidence was retrospectively estimated from all BP cases diagnosed between January 2000 and December 2005 in three French regions with a total population of 3.858 million inhabitants. BP mortality was assessed from a prospective cohort accrued during the same time period. A total of 502 incident BP patients (mean age: 82.6±8.8 years) were identified. Overall estimated incidence was 21.7 cases per million persons per year (95%CI:19.8-23.7 cases per million persons per year), which is about 3-fold higher than the incidence that we estimated 15 years ago. In the population aged 70 years or above, BP incidence was 162 cases per million per year (95%CI:147-177 cases per million per year). The overall 1-year survival rate was 62% (95% CI: 56-67%). The risk of death for BP patients was more than six times greater than that for the general population (SMR:6.60; 95%CI:5.47-7.90). The incidence of BP in France has increased 3-fold in the last 15 years. BP is associated with high mortality.
File Format	HTM / HTML
ISSN	0022202X
e-ISSN	15231747
Journal	Journal of Investigative Dermatology
Issue Number	8
Volume Number	132
Language	English
Publisher	Elsevier
Publisher Date	2012-08-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Dermatology Pemphigoid, Bullous Epidemiology Mortality Cohort Studies Models, Statistical Prospective Studies
Content Type	Text
Resource Type	Article
Subject	Cell Biology Biochemistry Molecular Biology Dermatology

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