NDLI: More than 300 consecutive living donor liver transplants a year at a single center.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Moon, D-B Lee, S-G Hwang, S. Kim, K-H Ahn, C-S Ha, T-Y Song, G-W Jung, D-H Park, G-C Namkoong, J-M Park, H-W Park, Y-H Park, C-S
Spatial Coverage	Republic of Korea
Description	Author Affiliation: Moon DB ( Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.)
Abstract	BACKGROUND: Living donor liver transplantation (LDLT) has been the first option for the patients requiring liver transplantation in East Asia because of the scarcity of cadaveric grafts. We have performed consecutively more than 300 LDLTs per year, and herein report our methods. METHODS: In 1997, the first successful adult LDLTs used a left and subsequently a right lobe. However, congestion in the anterior segment of right-lobe grafts prompted us to initiate reconstruction of middle hepatic venous tributaries in 1998. Dual LDLT grafts using 2 left lobes were developed in 2000 to solve graft-size insufficiency and minimize donor risk. The indications for adult LDLT were broadened to near complete obstruction of the portal vein by application of intraoperative cine-portography and portal vein stenting in 2004. ABO-incompatible adult LDLT was initiated in 2008 to overcome the blood group barrier between recipient and donor. RESULTS: With various innovations at our institution, 317 LDLTs were performed yearly in 2010 and 2011: 301 in 2010 and 298 in 2011. The most common primary diseases was hepatitis B virus-related liver cirrhosis with or without hepatocellular carcinoma (64.3%). The most common graft types were right hemiliver (82.6%). There has been no donor mortality. ABO-incompatible LDLT cases were 11.0% of the total. In-hospital mortality in 2011 was 2.5% (n = 8; adult 6, pediatric 2). CONCLUSION: Innovations in operative techniques and perioperative care as well as dedicated team members have made it possible to perform more than 300 LDLTs per year consecutively with excellent outcomes.
File Format	HTM / HTML
ISSN	00411345
Issue Number	5
Journal	Transplantation Proceedings
Volume Number	45
e-ISSN	18732623
Language	English
Publisher	Elsevier
Publisher Date	2013-06-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Transplantation__semicolon__medicine Liver Transplantation Statistics & Numerical Data Living Donors Adult Humans Republic Of Korea Journal Article
Content Type	Text
Resource Type	Article
Subject	Transplantation Surgery

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