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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Kengne, Andre Pascal Libend, Christelle Nong Dzudie, Anastase Menanga, Alain Dehayem, Mesmin Yefou Kingue, Samuel Sobngwi, Eugene |
| Spatial Coverage | Cameroon |
| Description | Country affiliation: South Africa Author Affiliation: Kengne AP ( South African Medical Research Council & University of Cape Town, Cape Town, South Africa.); Libend CN ( Diabetes and Endocrine service, Yaounde Central Hospital, Yaounde, Cameroon.); Dzudie A ( Service of Internal Medicine, General Hospital of Douala, Douala, & Buea faculty of Health Sciences, Buea, Cameroon.); Menanga A ( Service of Medicine A, General Hospital of Yaounde, Yaounde, Cameroon.); Dehayem MY ( Diabetes and Endocrine service, Yaounde Central Hospital, Yaounde, Cameroon.); Kingue S ( Service of Medicine A, General Hospital of Yaounde, Yaounde, Cameroon.); Sobngwi E ( Diabetes and Endocrine service, Yaounde Central Hospital, Yaounde, Cameroon.) |
| Abstract | INTRODUCTION: Ambulatory blood pressure (BP) measurements (ABPM) predict health outcomes better than office BP, and are recommended for assessing BP control, particularly in high-risk patients. We assessed the performance of office BP in predicting optimal ambulatory BP control in sub-Saharan Africans with type 2 diabetes (T2DM). METHODS: Participants were a random sample of 51 T2DM patients (25 men) drug-treated for hypertension, receiving care in a referral diabetes clinic in Yaounde, Cameroon. A quality control group included 46 non-diabetic individuals with hypertension. Targets for BP control were systolic (and diastolic) BP. RESULTS: Mean age of diabetic participants was 60 years (standard deviation: 10) and median duration of diabetes was 6 years (min-max: 0-29). Correlation coefficients between each office-based variable and the 24-h ABPM equivalent (diabetic vs. non-diabetic participants) were 0.571 and 0.601 for systolic (SBP), 0.520 and 0.539 for diastolic (DBP), 0.631 and 0.549 for pulse pressure (PP), and 0.522 and 0.583 for mean arterial pressure (MAP). The c-statistic for the prediction of optimal ambulatory control from office-BP in diabetic participants was 0.717 for SBP, 0.494 for DBP, 0.712 for PP, 0.582 for MAP, and 0.721 for either SBP + DBP or PP + MAP. Equivalents in diabetes-free participants were 0.805, 0.763, 0.695, 0.801 and 0.813. CONCLUSION: Office DBP was ineffective in discriminating optimal ambulatory BP control in diabetic patients, and did not improve predictions based on office SBP alone. Targeting ABPM to those T2DM patients who are already at optimal office-based SBP would likely be more cost effective in this setting. |
| File Format | HTM / HTML |
| e-ISSN | 19378688 |
| DOI | 10.11604/pamj.2014.19.231.2608 |
| Journal | Pan African Medical Journal |
| Volume Number | 19 |
| Language | English |
| Publisher | African Field Epidemiology Network |
| Publisher Date | 2014-01-01 |
| Publisher Place | Uganda |
| Access Restriction | Open |
| Subject Keyword | Discipline Medicine Antihypertensive Agents Therapeutic Use Blood Pressure Determination Diabetes Mellitus, Type 2 Physiopathology Hypertension Diagnosis Blood Pressure Drug Effects Blood Pressure Monitoring, Ambulatory Cameroon Cross-sectional Studies Drug Therapy |
| Content Type | Text |
| Resource Type | Article |
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