NDLI: Analysis of human plasma lipids by using comprehensive two-dimensional gas chromatography with dual detection and with the support of high-resolution time-of-flight mass spectrometry for structural elucidation.

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Analysis of human plasma lipids by using comprehensive two-dimensional gas chromatography with dual detection and with the support of high-resolution time-of-flight mass spectrometry for structural elucidation.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Salivo, Simona Beccaria, Marco Sullini, Giuseppe Tranchida, Peter Q. Dugo, Paola Mondello, Luigi
Description	Country affiliation: Italy Author Affiliation: Salivo S ( Dipartimento di Scienze del Farmaco e Prodotti per la Salute (S.C.I.F.A.R.), University of Messina, Viale Annunziata, Messina, Italy.)
Abstract	The main focus of the present research is the analysis of the unsaponifiable lipid fraction of human plasma by using data derived from comprehensive two-dimensional gas chromatography with dual quadrupole mass spectrometry and flame ionization detection. This approach enabled us to attain both mass spectral information and analyte percentage data. Furthermore, gas chromatography coupled with high-resolution time-of-flight mass spectrometry was used to increase the reliability of identification of several unsaponifiable lipid constituents. The synergism between both the high-resolution gas chromatography and mass spectrometry processes enabled us to attain a more in-depth knowledge of the unsaponifiable fraction of human plasma. Additionally, information was attained on the fatty acid and triacylglycerol composition of the plasma samples, subjected to investigation by using comprehensive two-dimensional gas chromatography with dual quadrupole mass spectrometry and flame ionization detection and high-performance liquid chromatography with atmospheric pressure chemical ionization quadrupole mass spectrometry, respectively.
File Format	HTM / HTML
ISSN	16159306
Issue Number	2
Journal	Journal of Separation Science
Volume Number	38
e-ISSN	16159314
Language	English
Publisher	Wiley-VCH
Publisher Date	2015-01-01
Publisher Place	Germany
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Analytical Discipline Chemistry Chromatography, Gas Methods Fatty Acids Blood Gas Chromatography-mass Spectrometry Triglycerides Humans Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Analytical Chemistry Filtration and Separation

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