| Content Provider |
World Health Organization (WHO)-Global Index Medicus |
| Author |
Huang, Chin-Ying Lai, Wan-Yu Sun, Mao-Feng Lin, Che-Chen Chen, Bor-Chyuan Lin, Hung-Jen Chang, Ching-Mao Yang, Chung-Hsien Huang, Kuo-Chin Yen, Hung-Rong |
| Spatial Coverage |
Taiwan |
| Description |
Country affiliation: Taiwan Author Affiliation: Huang CY ( Research Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, 2 Yude Road, North District, Taichung 404, Taiwan); Lai WY ( Department of Traditional Chinese Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan); Sun MF ( Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan); Lin CC ( Health Data Management Office, China Medical University Hospital, Taichung, Taiwan.); Chen BC ( Department of Chinese Medicine, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan.); Lin HJ ( Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan); Chang CM ( Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan); Yang CH ( Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan); Huang KC ( Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan); Yen HR ( Research Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, 2 Yude Road, North District, Taichung 404, Taiwan) |
| Abstract |
ETHNOPHARMACOLOGICAL RELEVANCE: Peptic ulcer disease is a common digestive disease. There is a lack of large-scale survey on the use of traditional Chinese medicine (TCM) for the treatment of peptic ulcer disease. This study aimed to investigate the utilization of TCM for the treatment of peptic ulcer disease in Taiwan. MATERIALS AND METHODS: We analyzed a random sample comprised of one million individuals with newly diagnosed peptic ulcer disease between 2001 and 2010 from the National Health Insurance Research Database in Taiwan. Demographic characteristics and TCM usage, including Chinese herbal formulas and the single herbs prescribed for patients with peptic ulcer disease, were analyzed. RESULTS: A total of 96,624 newly diagnosed subjects with peptic ulcer disease were included. 14,983 (15.5%) patients were TCM users. People residing in highly urbanized areas, younger people and female (compared with male) were more likely to use TCM. With regard to the comorbidities, TCM users had a lower prevalence of coronary artery disease, chronic obstructive lung disease, diabetes mellitus and liver cirrhosis and stroke. The average time between onset of peptic ulcer disease and the first visit to a TCM clinic was 4.7 months. Majority of the patients (n=14,449; 96.4%) received only Chinese herbal remedies. The most frequently prescribed Chinese herbal formula and single herb was Ban-Xia-Xie-Xin-Tang (Pinelliae Decoction to Drain the Epigastrium) and Hai-Piao-Xiao (Os Sepiae), respectively. The core pattern analysis showed that combination of Ban-Xia-Xie-Xin-Tang, Hai-Piao-Xiao (Os Sepiae), Yan-Hu-Suo (Rhizoma Corydalis), Bei-Mu (Bulbus Fritillariae Thunbergii) and Chuan-Lian-Zi (Fructus Toosendan) was most frequently used for peptic ulcer disease. CONCLUSIONS: Our study identified the core prescription patterns of TCM for patients with peptic ulcer disease in Taiwan. Further basic and clinical studies are necessary to elucidate the efficacy and mechanisms. |
| File Format |
HTM / HTML |
| ISSN |
03788741 |
| Volume Number |
176 |
| e-ISSN |
18727573 |
| Journal |
Journal of Ethnopharmacology |
| Language |
English |
| Publisher |
Elsevier |
| Publisher Date |
2015-12-24 |
| Publisher Place |
Ireland |
| Access Restriction |
One Nation One Subscription (ONOS) |
| Subject Keyword |
Discipline Ethnopharmacology Drugs, Chinese Herbal Therapeutic Use Peptic Ulcer Drug Therapy Physician's Practice Patterns Statistics & Numerical Data Adult Female Humans Male Medicine, Chinese Traditional Middle Aged Taiwan Young Adult Journal Article Research Support, Non-u.s. Gov't |
| Content Type |
Text |
| Resource Type |
Article |
| Subject |
Drug Discovery Pharmacology |
