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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Knapp, Charles W. Zhang, Wen Sturm, Belinda S. M. Graham, David W. |
| Description | Country affiliation: United kingdom Author Affiliation: Knapp CW ( David Livingstone Centre for Sustainability, Department of Civil Engineering, University of Strathclyde, 50 Richmond Street, Glasgow, G1 1XN, UK. charles.knapp@strath.ac.uk) |
| Abstract | The attenuation and fate of erythromycin-resistance-methylase (erm) and extended-spectrum beta-lactamse (bla) genes were quantified over time in aquatic systems by adding 20-L swine waste to 11,300-L outdoor mesocosms that simulated receiving water conditions below intensive agricultural operations. The units were prepared with two different light-exposure scenarios and included artificial substrates to assess gene movement into biofilms. Of eleven genes tested, only erm(B), erm(F), bla(SHV) and bla(TEM) were found in sufficient quantity for monitoring. The genes disappeared rapidly from the water column and first-order water-column disappearance coefficients were calculated. However, detected gene levels became elevated in the biofilms within 2 days, but then disappeared over time. Differences were observed between sunlight and dark treatments and among individual genes, suggesting that ecological and gene-specific factors play roles in the fate of these genes after release into the environment. Ultimately, this information will aid in generating better predictive models for gene fate. |
| File Format | HTM / HTML |
| ISSN | 02697491 |
| Issue Number | 5 |
| Volume Number | 158 |
| e-ISSN | 18736424 |
| Journal | Environmental Pollution |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2010-05-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Environmental Discipline Science Bacteria Genetics Bacterial Proteins Drug Resistance, Multiple, Bacterial Feces Microbiology Animals Anti-bacterial Agents Pharmacology Drug Effects Isolation & Purification Metabolism Bacterial Physiological Phenomena Biofilms Erythromycin Sewage Chemistry Swine Beta-lactam Resistance Journal Article Research Support, Non-u.s. Gov't Research Support, U.s. Gov't, Non-p.h.s. |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health, Toxicology and Mutagenesis Pollution Medicine Toxicology |
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