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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Cadel-Six, Sabrina Moyenga, David Magny, Stéphanie Trotereau, Sophie Edery, Marc Krys, Sophie |
| Description | Author Affiliation: Cadel-Six S ( Unité de Caractérisation des Toxines, ANSES, 23 avenue du Général de Gaulle, 94706 Maisons-Alfort, France. Electronic address: sabrina.cadelsix@anses.fr.); Moyenga D ( UMR 7245 CNRS-MNHN Molécules de Communication et Adaptation des Micro-organismes, Muséum National d'Histoire Naturelle, 12 rue Buffon, F-75231 Paris Cedex 05, France.); Magny S ( Unité de Caractérisation des Toxines, ANSES, 23 avenue du Général de Gaulle, 94706 Maisons-Alfort, France.); Trotereau S ( Unité de Caractérisation des Toxines, ANSES, 23 avenue du Général de Gaulle, 94706 Maisons-Alfort, France.); Edery M ( UMR 7245 CNRS-MNHN Molécules de Communication et Adaptation des Micro-organismes, Muséum National d'Histoire Naturelle, 12 rue Buffon, F-75231 Paris Cedex 05, France.); Krys S ( Unité de Caractérisation des Toxines, ANSES, 23 avenue du Général de Gaulle, 94706 Maisons-Alfort, France.) |
| Abstract | So far only a few publications have explored the development of extraction methods of cyanotoxin extracted from complex matrices. With regard to cyanobacterial microcystins (MCs), the data on the contamination of the flesh of aquatic organisms is hard to compare and very limited due to the lack of validated methods. In recent years, evidence that both free and bound fractions of toxin are found in these tissues has highlighted the need to develop effective methods of quantification. Several techniques do exist, but only the Lemieux oxidation has so far been used to investigate complex tissue matrices. In this study, protocols based on the Lemieux approach were adapted for the quantitative chemical analysis of free MC-LR and MMPB derived from bound toxin in the tissues of juvenile trout gavaged with MC-LR. Afterwards, the NF V03 110 guideline was used to characterize the protocols elaborated and evaluate their effectiveness. |
| File Format | HTM / HTML |
| ISSN | 02697491 |
| Volume Number | 185 |
| e-ISSN | 18736424 |
| Journal | Environmental Pollution |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2014-02-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Environmental Discipline Science Microcystins Metabolism Oncorhynchus Mykiss Water Pollutants, Chemical Animals Chemical Phenomena Chromatography, Liquid Gills Humans Intestines Liver Chemistry Tandem Mass Spectrometry Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health, Toxicology and Mutagenesis Pollution Medicine Toxicology |
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