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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Fujii, Yukiko Harada, Kouji H. Hitomi, Toshiaki Kobayashi, Hatasu Koizumi, Akio Haraguchi, Koichi |
| Spatial Coverage | Japan |
| Description | Country affiliation: Japan Author Affiliation: Fujii Y ( Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Yoshida, Kyoto 606-8501, Japan.); Harada KH ( Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Yoshida, Kyoto 606-8501, Japan.); Hitomi T ( Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Yoshida, Kyoto 606-8501, Japan.); Kobayashi H ( Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Yoshida, Kyoto 606-8501, Japan.); Koizumi A ( Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Yoshida, Kyoto 606-8501, Japan.); Haraguchi K ( Daiichi College of Pharmaceutical Sciences, Tamagawa-cho, Minami-ku, Fukuoka 815-8511, Japan. Electronic address: k-haraguti@daiichi-cps.ac.jp.) |
| Abstract | The temporal trend in serum concentrations of phenolic organohalogen contaminants (POCs) were investigated in two age groups of men from Kyoto, Japan, from 1989 to 2010. These concentrations and trends were compared with neutral contaminants including polychlorinated biphenyls (PCBs) and pesticides. Serum concentrations of pentachlorophenol (PenCP) and 4-hydroxy-PCB187 were age-dependent and decreased to approximately one-half during the two decades, whereas no contamination trends were observed for 2,4,6-tribromophenol (TriBP), tetrabromobisphenol A (TBBPA) and 6-hydroxy-2,2',4,4'-tetrabromodiphenyl ether (6-OH-BDE47). 6-OH-BDE47 was found in all samples (up to 3000 pg/g wet weight), whereas TBBPA was detected in 17 of 60 serum samples (up to 950 pg/g wet weight). The concentrations of TriBP, TBBPA and 6-OH-BDE47 were not correlated to those of PenCP or 4-OH-PCB187 in either age group, suggesting the different kinetics on exposure routes and fate between these brominated and chlorinated POCs. |
| File Format | HTM / HTML |
| ISSN | 02697491 |
| Volume Number | 185 |
| e-ISSN | 18736424 |
| Journal | Environmental Pollution |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2014-02-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Environmental Discipline Science Environmental Exposure Analysis Environmental Pollutants Blood Hydrocarbons, Halogenated Phenols Adult Statistics & Numerical Data Halogenated Diphenyl Ethers Humans Japan Male Middle Aged Pentachlorophenol Pesticides Polybrominated Biphenyls Polychlorinated Biphenyls Young Adult Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health, Toxicology and Mutagenesis Pollution Medicine Toxicology |
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