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| Content Provider | Taylor & Francis Online |
|---|---|
| Author | Guwatudde, David Volmink, Jimmy Nankya-Mutyoba, Joan Njelekela, Marina A. Reid, Todd G. Laurence, Carien Dalal, Shona Chiwanga, Faraja S. Adebamowo, Clement Bajunirwe, Francis Ajayi, IkeOluwapo Adami, Hans-Olov Diamond, Megan B. Holmes, Michelle D. Kalyesubula, Robert |
| Abstract | BackgroundThe increase in prevalence of diabetes and pre-diabetes in sub-Saharan Africa underlines the importance of understanding its magnitude and causes in different population groups. We analyzed data from the Africa/Harvard Partnership for Cohort Research and Training (PaCT) studies to determine the prevalence of diabetes and pre-diabetes and risk factors associated with diabetes.MethodologyParticipants were randomly selected from peri-urban (n=297) and rural (n=200) communities in Uganda, and teachers were recruited from schools (n=229) in urban Tanzania. We used a standardized questionnaire to collect socio-demographic and self-reported disease status including diabetes status. Blood glucose was also measured after participants fasted for 8 h. We used standard protocols for anthropometric and blood pressure measurement.ResultsThe overall prevalence of diabetes was 10.1% and was highest in rural Ugandan residents (16.1%) compared to teachers in Tanzania (8.3%) and peri-urban Ugandan residents (7.6%). The prevalence of pre-diabetes was 13.8%. The prevalence of self-reported diabetes was low across all sites, where 68% of participants with diabetes were not captured by self-report. In multivariable logistic regression analysis, family history (OR 2.5, 95% CI: 1.1, 5.6) and hypertension (OR 2.3, 95% CI: 1.1, 5.2) were significantly associated with diabetes.ConclusionsThe prevalence of diabetes and pre-diabetes in Uganda and Tanzania is high, differs markedly between population groups, and remains undiagnosed in an alarmingly high proportion of individuals. These findings highlight the need for large-scale, prospective studies to accurately quantify the burden and identify effective intervention and treatment strategies across diverse African populations. |
| File Format | PDF HTM / HTML |
| ISSN | 16549716 16549880 |
| DOI | 10.3402/gha.v9.31440 |
| Journal | Global Health Action |
| Volume Number | 9 |
| Issue Number | 1 |
| Language | English |
| Publisher | Taylor & Francis |
| Publisher Date | 2016-05-23 |
| Access Restriction | Open |
| Subject Keyword | Non-communicable Risk factors Underdiagnoses Sub-Saharan Africa Tanzania Uganda |
| Content Type | Text |
| Resource Type | Article |
| Subject | Public Health, Environmental and Occupational Health Health Policy |
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