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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Al-Mhanna, Sameer Badri Rocha-Rodriguesc, Sílvia Mohamed, Mahaneem Batrakoulis, Alexios Aldhahi, Monira I. Afolabi, Hafeez Abiola Yagin, Fatma Hilal Alhussain, Maha H. Gülü, Mehmet Abubakar, Bishir Daku Ghazali, Wan Syaheedah Wan Alghannam, Abdullah F. Badicu, Georgian |
| Abstract | Background Lifestyle modifications involving diet and exercise are recommended for patients diagnosed with obesity and type 2 diabetes mellitus (T2DM). The purpose of this review was to systematically evaluate the effects of combined aerobic exercise and diet (AEDT) on various cardiometabolic health-related indicators among individuals with obesity and T2DM. Methodology A comprehensive search of the PubMed/Medline, Web of Science, Scopus, Science Direct, Cochrane, and Google Scholar databases was conducted for this meta-analysis. The Cochrane risk of bias tool was used to evaluate eligible studies, and the GRADE tool was used to rate the certainty of evidence. A random-effects model for continuous variables was used, and the results were presented as mean differences or standardised mean differences with 95% confidence intervals. Results A total of 16,129 studies were retrieved; 20 studies were included, and data were extracted from 1,192 participants. The findings revealed significant improvements in body mass index, body weight, waist circumference, systolic blood pressure, diastolic blood pressure, total cholesterol, triglycerides, fasting blood glucose, fasting plasma insulin, glycated hemoglobin, leptin, interleukin-6, C-reactive protein, and adiponectin (p < 0.05) compared to the standard treatment (ST) group. No significant differences were observed between the AEDT and ST groups in fat mass, hip circumference, waist-to-hip ratio, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and tumor necrosis factor-alpha. The present findings are based on low- to moderate-quality evidence. Conclusions AEDT may be a critical behavior for holistic cardiometabolic health-related benefits as a contemporary anti-obesity medication due to its significant positive impact on patients with obesity and T2DM. Nevertheless, further robust evidence is necessary to determine whether AEDT is an effective intervention for lowering cardiovascular and metabolic risk factors among individuals with obesity and T2DM. |
| Related Links | https://bmcsportsscimedrehabil.biomedcentral.com/counter/pdf/10.1186/s13102-023-00766-5.pdf |
| Ending Page | 15 |
| Page Count | 15 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| ISSN | 20521847 |
| DOI | 10.1186/s13102-023-00766-5 |
| Journal | BMC Sports Science, Medicine and Rehabilitation |
| Issue Number | 1 |
| Volume Number | 15 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2023-12-04 |
| Access Restriction | Open |
| Subject Keyword | BMC Sports Science Medicine and Rehabilitation Sports Medicine Orthopedics Rehabilitation Medicine Physical activity Exercise Overweight Metabolic syndrome Lifestyle intervention |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physical Therapy, Sports Therapy and Rehabilitation Rehabilitation Orthopedics and Sports Medicine |
| Journal Impact Factor | 2.1/2023 |
| 5-Year Journal Impact Factor | 2.3/2023 |
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