NDLI: Ethnicity and survival in bladder cancer: a population-based study based on the SEER database

Content Provider	Springer Nature : BioMed Central
Author	Fang, Wei Yang, Zhi-Yan Chen, Ting-Yu Shen, Xian-Feng Zhang, Chao
Abstract	Background Bladder cancer is the most common cancer in the urinary system and the fourth most common cancer in males. This study aimed to examine differences in the survival of bladder cancer patients of different ethnicities. Method We used the SEER database to obtain data pertaining to bladder cancer patients from 2010 to 2015. Univariate and multivariate Cox proportional hazards regression analyses were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between ethnicity and death. Kaplan–Meier survival and nomogram analyses were used to compare survival differences among patients with different ethnicities. Results Among 101,364 bladder cancer patients, 90,910 were white, 5893 were black, 337 were American Indian/Alaska Native (AIAN), and 4224 were Asian or Pacific Islander (API). Our multivariate analysis identified differences between different ethnicities. Compared to the API group, the AIAN (HR = 1.31, 95% CI = 1.09–1.57, P < 0.001), black (HR = 1.56, 95% CI = 1.46–1.67, P < 0.001), and white (HR = 1.18, 95% CI = 1.12–1.25, P < 0.001) groups showed lower survival probabilities. Based on data from all Kaplan–Meier survival curves, there was no significant difference in survival between the black and AIAN groups, but the survival of these two races was worse than that of the white and API groups. We also used a nomogram to estimate patient survival and validated its predictive value. Conclusion Our results suggest that ethnic differences exist in patients with bladder cancer, that the survival of black and AIAN bladder cancer patients is worse than that of other ethnicities and that the survival of API patients is the best. The significant prognostic factors of overall survival, which include age, sex, ethnicity, summary stage, American Joint Committee on Cancer stage, surgery type, and histologic type, should be applied to bladder cancer patient prognostication.
Related Links	https://translational-medicine.biomedcentral.com/counter/pdf/10.1186/s12967-020-02308-w.pdf
Ending Page	11
Page Count	11
Starting Page	1
File Format	HTM / HTML
ISSN	14795876
DOI	10.1186/s12967-020-02308-w
Journal	Journal of Translational Medicine
Issue Number	1
Volume Number	18
Language	English
Publisher	BioMed Central
Publisher Date	2020-03-30
Access Restriction	Open
Subject Keyword	Biomedicine Medicine Public Health Bladder cancer Ethnic Survival rate Kaplan–Meier survival SEER database Medicine/Public Health
Content Type	Text
Resource Type	Article
Subject	Biochemistry, Genetics and Molecular Biology Medicine
Journal Impact Factor	6.1/2023
5-Year Journal Impact Factor	6.3/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Ethnicity and survival in bladder cancer: a population-based study based on the SEER database

Survival in sinonasal and middle ear malignancies: a population-based study using the SEER 1973-2015 database.

Survival differences by ethnicity among patients diagnosed with bladder cancer

Benefits of local tumor excision and pharyngectomy on the survival of nasopharyngeal carcinoma patients: a retrospective observational study based on SEER database

PROGgeneV2: enhancements on the existing database

Prognostic nomogram for bladder cancer with brain metastases: a National Cancer Database analysis

Head & neck acinar cell carcinoma: a population-based study using the seer registry

Unstaged cancer in the United States: a population-based study

A web-based prediction model for overall survival of elderly patients with early renal cell carcinoma: a population-based study

Ethnicity and survival in bladder cancer: a population-based study based on the SEER database

Similar Documents

Ethnicity and survival in bladder cancer: a population-based study based on the SEER database

Survival in sinonasal and middle ear malignancies: a population-based study using the SEER 1973-2015 database.

Survival differences by ethnicity among patients diagnosed with bladder cancer

Benefits of local tumor excision and pharyngectomy on the survival of nasopharyngeal carcinoma patients: a retrospective observational study based on SEER database

PROGgeneV2: enhancements on the existing database

Prognostic nomogram for bladder cancer with brain metastases: a National Cancer Database analysis

Head & neck acinar cell carcinoma: a population-based study using the seer registry

Unstaged cancer in the United States: a population-based study

A web-based prediction model for overall survival of elderly patients with early renal cell carcinoma: a population-based study

Ethnicity and survival in bladder cancer: a population-based study based on the SEER database