NDLI: Measuring the disease burden of seasonal influenza in Germany 2015 - 2020 using the incidence-based disability-adjusted life years (DALYs)

Content Provider	Springer Nature : BioMed Central
Author	Stapic, Marin Schulz, Ricarda Sophia Tamayo-Cuartero, Elena Kurth, Tobias Brinks, Ralph
Abstract	Background Seasonal influenza can lead to severe complications and death, resulting in high disease burden each year. The European Centre for Disease Prevention and Control introduced the Burden of Communicable diseases in Europe (BCoDE) project, quantifying the disease burden of infectious diseases in disability-adjusted life years (DALY). DALYs for influenza exceed those of Tuberculosis, HIV, and Invasive pneumococcal disease. As data on disease burden are limited, this study aims to calculate the seasonal influenza burden for Germany between 2015 and 2020. Methods The BCoDE-toolkit developed by the European Centre for Disease Prevention and Control was used, calculating country-specific DALYs. Information on incidence, population data, and underestimation were taken from the Robert Koch-Institute and the Federal Statistical Office of Germany. Outcome trees were created based on information from a rapid review and previous publications. Baseline, lower-bound and upper-bound scenarios were developed to assess the disease burden under varying conditions. Results Estimates range from 127,100 DALYs (153 DALYs per 100,000 population) and 1,171,115 DALYs (1,414 DALYs per 100,000 population) depending on the scenario and year examined. The main contributors to the disease burden are sequelae, primarily pneumonia, encephalitis, and myocarditis. The highest burden estimates are observable for infants, children under the age of five and the elderly. Conclusions Using a composite health measure like DALY can offer valuable insight into a disease’s impact on population health. Our results indicate a high disease burden due to seasonal influenza in Germany, indicating further research into complication rates, underestimation, and intervention programs for vulnerable populations, e.g., vaccination in infants, children under age of five and elderly population.
Related Links	https://bmcinfectdis.biomedcentral.com/counter/pdf/10.1186/s12879-025-10613-2.pdf
Ending Page	11
Page Count	11
Starting Page	1
File Format	HTM / HTML
ISSN	14712334
DOI	10.1186/s12879-025-10613-2
Journal	BMC Infectious Diseases
Issue Number	1
Volume Number	25
Language	English
Publisher	BioMed Central
Publisher Date	2025-03-26
Access Restriction	Open
Subject Keyword	Infectious Diseases Parasitology Medical Microbiology Tropical Medicine Internal Medicine Influenza Disability-adjusted life years Infectious disease surveillance Communicable diseases Burden of disease Population health
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases
Journal Impact Factor	3.4/2023
5-Year Journal Impact Factor	3.3/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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