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  1. Journal of the Korean Society for Applied Biological Chemistry
  2. Journal of the Korean Society for Applied Biological Chemistry : Volume 58
  3. Journal of the Korean Society for Applied Biological Chemistry : Volume 58, Issue 1, February 2015
  4. Flavonoids activating adenosine monophosphate-activated protein kinase
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Journal of the Korean Society for Applied Biological Chemistry : Volume 60
Journal of the Korean Society for Applied Biological Chemistry : Volume 59
Journal of the Korean Society for Applied Biological Chemistry : Volume 58
Journal of the Korean Society for Applied Biological Chemistry : Volume 58, Issue 6, December 2015
Journal of the Korean Society for Applied Biological Chemistry : Volume 58, Issue 5, October 2015
Journal of the Korean Society for Applied Biological Chemistry : Volume 58, Issue 4, August 2015
Journal of the Korean Society for Applied Biological Chemistry : Volume 58, Issue 3, June 2015
Journal of the Korean Society for Applied Biological Chemistry : Volume 58, Issue 2, April 2015
Journal of the Korean Society for Applied Biological Chemistry : Volume 58, Issue 1, February 2015
Analysis of alkanethiolates on gold with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Phototactic behavior 6: behavioral responses of Myzus persicae (Hemiptera: Aphididae) to light-emitting diodes
Flavonoids activating adenosine monophosphate-activated protein kinase
Differentiation of highbush blueberry (Vaccinium corymbosum L.) fruit cultivars by GC–MS-based metabolic profiling
Enhanced saccharification of reed and rice straws by the addition of β-1,3-1,4-glucanase with broad substrate specificity and calcium ion
Long-term fate of the herbicide mefenacet in a rice-grown lysimeter over a period of 6 consecutive years
Fructooligosaccharides decreased the ability of probiotic Escherichia coli Nissle 1917 to adhere to co-cultures of human intestinal cell lines
Effect of lotus seed and seedpod extracts on oxidative stability against lard during storage
Development of a PCR-based assay to differentiate Cervus elaphus sibiricus from Cervus antlers
Volatile compounds of ginseng (Panax sp.): a review
Identification of flavonoids from Eriodictyon californicum and their cytotoxicity against HCT116 colon cancer cells
Preparation of perilla seed meal protein composite films containing various essential oils and their application in sausage packaging
Analgesic anti-inflammatory anti-pyretic activities of Garcinia hydroxybiflavanonol (GB1) from Garcinia kola
Effects of oven drying on pesticide residues in field-grown chili peppers
The synthetic compound 2′-hydroxy-2,4,6′-trimethoxychalcone overcomes P-glycoprotein-mediated multi-drug resistance in drug-resistant uterine sarcoma MES-SA/DX5 cells
Antifungal activity of Streptomyces albidoflavus L131 against the leaf mold pathogen Passalora fulva involves membrane leakage and oxidative damage
Antimicrobial activities of 1,2-dihydroxyanthraquinone derivatives against food-borne bacteria
Blueberry extract inhibits carbohydrate-hydrolyzing enzymes and these inhibitory activities are not proanthocyanidin dependent
LC–MS/MS monitoring of 22 illegal antihistamine compounds in health food products from the Korean market
Effects of ultraviolet radiation on the physicochemical characteristics of Korean native cattle (Hanwoo) beef
Erratum to: Classification of Korean Chrysanthemum species based on volatile compounds using cluster analysis and principal component analysis
Erratum to: A putative cold shock protein-encoding gene isolated from Arthrobacter sp. A2-5 confers cold stress tolerance in yeast and plants
Journal of the Korean Society for Applied Biological Chemistry : Volume 57
Journal of the Korean Society for Applied Biological Chemistry : Volume 56
Journal of the Korean Society for Applied Biological Chemistry : Volume 55
Journal of the Korean Society for Applied Biological Chemistry : Volume 54
Journal of the Korean Society for Applied Biological Chemistry : Volume 53
Journal of the Korean Society for Applied Biological Chemistry : Volume 52

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Flavonoids activating adenosine monophosphate-activated protein kinase

Content Provider Springer Nature Link
Author Shin, Soon Young Chong, Youhoon Ahn, Seunghyun Jung, Hyeryoung Lim, Yoongho Yong, Yeonjoong Jung, Yearam
Copyright Year 2015
Abstract Eighteen flavonoids were tested as adenosine monophosphate-activated protein kinase (AMPK) activators. The AMPK activation induced by kaempferide was 1.75 times better than the value obtained at 100 % AMPK phosphorylation. Western blotting analysis of kaempferide demonstrated that it increased the phosphorylation of AMPK in vitro. In silico docking results carried out to elucidate the binding mode between kaempferide and AMPK showed the docking pose of kaempferide in the binding site of AMPK was similar to that of the substrate contained in the crystallographic structure of AMPK. Flavonoids, including kaempferide, are promising potential AMPK activators.
Starting Page 13
Ending Page 19
Page Count 7
File Format PDF
ISSN 17382203
Journal Journal of the Korean Society for Applied Biological Chemistry
Volume Number 58
Issue Number 1
e-ISSN 2234344X
Language English
Publisher Springer Netherlands
Publisher Date 2015-01-20
Publisher Place Dordrecht
Access Restriction Subscribed
Subject Keyword Kinase assay Kaempferide Applied Microbiology AMPK In silico docking Biological Techniques Flavonoid Bioorganic Chemistry
Content Type Text
Resource Type Article
Subject Organic Chemistry Biochemistry, Genetics and Molecular Biology
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