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A comparison of mathematical models of left ventricular contractility derived from aortic blood flow velocity and acceleration: Application to the esophageal doppler monitor

Biomedical Engineering Letters : Volume 4, Issue 2, June 2014

Biomedical Engineering Letters : Volume 4, Issue 1, March 2014

Biomedical Engineering Letters : Volume 3

Biomedical Engineering Letters : Volume 2

Biomedical Engineering Letters : Volume 1

A comparison of mathematical models of left ventricular contractility derived from aortic blood flow velocity and acceleration: Application to the esophageal doppler monitor

Content Provider	Springer Nature Link
Author	Atlas, Glen Li, John K J. Kostis, John B.
Copyright Year	2014
Abstract	The esophageal Doppler monitor (EDM) has traditionally been used for minimally-invasive and continuous assessment of both cardiac output and intravascular volume. These measurements are based upon a beat-to-beat analysis of the velocity of distal thoracic aortic blood flow. The purpose of this paper is to compare different mathematical models of LV contractile function which could utilize the EDM and subsequently be determined on a continuous basis.This study investigated velocity-based contractility models: peak velocity, (PV); ejection fraction, EF; mean ejection fraction, $\overline {EF} $ ; and maximum LV radial shortening velocity, $$max\left\| {\frac{{dR}}{{dt}}} \right\|$$ . Also examined are acceleration-based models: mean acceleration, (MA); force, (F); the maximum rate of rise of systolic arterial blood pressure, $$max\left( {\frac{{dP}}{{dt}}} \right)$$ ; and kinetic energy, (KE).When normalized and subsequently observed on a dimensionless basis, acceleration-based models appear to have a statistically significant greater sensitivity to changes in LV contractility. Furthermore, by combining simultaneous arterial blood pressure measurements with EDM-based flow information, the components of afterload and their effects on LV contractility could be estimated.Future research is warranted to determine the applicability and limitations of the EDM in continuous assessment of LV contractility and related hemodynamic parameters.
Starting Page	301
Ending Page	315
Page Count	15
File Format	PDF
ISSN	20939868
Journal	Biomedical Engineering Letters
Volume Number	4
Issue Number	3
e-ISSN	2093985X
Language	English
Publisher	The Korean Society of Medical and Biological Engineering
Publisher Date	2014-10-18
Publisher Place	Korea
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Esophageal Doppler monitor Cardiac contractility Force Kinetic energy Heart failure Modeling Biomedical Engineering Biophysics and Biological Physics Biomedicine general Medical and Radiation Physics
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering

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