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| Content Provider | Springer Nature Link |
|---|---|
| Author | El Gohary, Sherif Hamdy Metwally, Mohamed Kilany Eom, Seyoung Jeon, Seung Hyun Byun, Kyung Min Kim, Tae Seong |
| Copyright Year | 2014 |
| Abstract | In this work, we propose an alternative photoacoustic probe based on transurethral laser illumination to a conventional transrectal photoacoustic imaging system suffering from a high optical absorption at a rectal wall and its surrounding tissues.We validate improved performance of the proposed scheme using 3-dimensional prostate model and analytical calculations such as Monte Carlo simulation and finite element method (FEM). Monte Carlo simulation and FEM are used to find the absorption profiles of photons and the accompanying temperature elevation and pressure signal generation.It is found that light source inside the urethra and ultrasound transducer on the rectal wall is an optimal combination to produce a high amplitude in pressure signal and a high signal-to-noise ratio in the reconstructed image. Design study on light source geometry such as beam shape, beam size and gap distance between two light sources is also performed to improve an absorption efficiency at the prostate cancer.Our study will be helpful in determining an optimized probe design of photoacoustic imaging system for advancing the detection of prostate cancer. |
| Starting Page | 250 |
| Ending Page | 257 |
| Page Count | 8 |
| File Format | |
| ISSN | 20939868 |
| Journal | Biomedical Engineering Letters |
| Volume Number | 4 |
| Issue Number | 3 |
| e-ISSN | 2093985X |
| Language | English |
| Publisher | The Korean Society of Medical and Biological Engineering |
| Publisher Date | 2014-10-18 |
| Publisher Place | Korea |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Photoacoustic detection Prostate cancer 3-Dimensional Monte Carlo simulation Finite element method Transurethral laser illumination Geometry optimization of light source Biomedical Engineering Biophysics and Biological Physics Biomedicine general Medical and Radiation Physics |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biomedical Engineering |
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