NDLI: Comparison of gene expression changes induced by exposure to Ag, Cu-TiO$_{2}$, and TiO$

Content Provider	Springer Nature Link
Author	Park, Hyung Geun Yeo, Min Kyeong
Copyright Year	2013
Abstract	Nanomaterials composed of silver (Ag), copper-doped titanium dioxide (Cu-TiO$_{2}$), and pure titanium dioxide (TiO$_{2}$) have wide applications in consumer products such as cosmetics, electronic appliances, clothes, and industry materials such as solar cell. However, there are problems associated with the exposure of aquatic organisms in the ecosystem to such nanomaterials. In this study, we investigated the expression pattern of genes in zebrafish embryos after exposure to nanomaterials. We used several functional categories including apoptosis, endocytosis, immune response, and endoplasmic reticulum stress so on. A total of 314 (278 up-regulated and 36 down-regulated), 283 (129 up-regulated and 154 down-regulated), and 360 (198 up-regulated and 162 down-regulated) genes were differentially expressed in zebrafish embryos exposed to Ag, Cu-TiO$_{2}$, and TiO$_{2}$ NPs, respectively, with apoptosis being the function of the highest proportion of differentially expressed genes in all 3 NP exposures. Our data provide a basis for conducting further mechanistic studies of genes that are induced or suppressed upon exposure to NPs in zebrafish embryogenesis.
Starting Page	129
Ending Page	139
Page Count	11
File Format	PDF
ISSN	1738642X
Journal	Molecular & Cellular Toxicology
Volume Number	9
Issue Number	2
e-ISSN	20928467
Language	English
Publisher	Springer Netherlands
Publisher Date	2013-07-18
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Ag nanoparticles Cu-TiO$_{2}$ nanoparticles TiO$_{2}$ nanoparticles Apoptosis Zebrafish embryos Cell Biology Pharmacology/Toxicology
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health Toxicology Pathology and Forensic Medicine

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Gene expression in zebrafish embryos following exposure to TiO$_{2}$ nanoparticles

Gene expression in zebrafish embryos following exposure to Cu-doped TiO$_{2}$ and pure TiO$_{2}$ nanometer-sized photocatalysts

The effect of metal-doped TiO$_{2}$ nanoparticles on zebrafish embryogenesis

Effects of TiO$_{2}$ nanoparticles and nanotubes on zebrafish caudal fin regeneration

Metabolic gene expression profiling of Zebrafish embryos exposed to silver nanocolloids and nanotubes

The effects of TiO$_{2}$ nanoparticles on the protein expression in mouse lung

The biological toxicities of two crystalline phases and differential sizes of TiO$_{2}$ nanoparticles during zebrafish embryogenesis development

Comparison of gene expression patterns from zebrafish embryos between pure silver nanomaterial and mixed silver nanomaterial containing cells of Hydra magnipapillata

Proteomic profiling of the differentially expressed proteins by TiO$_{2}$ nanoparticles in mouse kidney

Comparison of gene expression changes induced by exposure to Ag, Cu-TiO$_{2}$, and TiO$_{2}$ nanoparticles in zebrafish embryos

Similar Documents

Gene expression in zebrafish embryos following exposure to TiO$_{2}$ nanoparticles

Gene expression in zebrafish embryos following exposure to Cu-doped TiO$_{2}$ and pure TiO$_{2}$ nanometer-sized photocatalysts

The effect of metal-doped TiO$_{2}$ nanoparticles on zebrafish embryogenesis

Effects of TiO$_{2}$ nanoparticles and nanotubes on zebrafish caudal fin regeneration

Metabolic gene expression profiling of Zebrafish embryos exposed to silver nanocolloids and nanotubes

The effects of TiO$_{2}$ nanoparticles on the protein expression in mouse lung

The biological toxicities of two crystalline phases and differential sizes of TiO$_{2}$ nanoparticles during zebrafish embryogenesis development

Comparison of gene expression patterns from zebrafish embryos between pure silver nanomaterial and mixed silver nanomaterial containing cells of Hydra magnipapillata

Proteomic profiling of the differentially expressed proteins by TiO$_{2}$ nanoparticles in mouse kidney

Comparison of gene expression changes induced by exposure to Ag, Cu-TiO$_{2}$, and TiO$_{2}$ nanoparticles in zebrafish embryos