NDLI: A Comparative Evaluation of Antimicrobial Effect of Thymus capitatus Ethanolic Extract on the Different Respiratory Tract Infections Isolates

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A Comparative Evaluation of Antimicrobial Effect of Thymus capitatus Ethanolic Extract on the Different Respiratory Tract Infections Isolates

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A Comparative Evaluation of Antimicrobial Effect of Thymus capitatus Ethanolic Extract on the Different Respiratory Tract Infections Isolates

Content Provider	Springer Nature Link
Author	Hassan, Gamal Osman Karamova, Nazira Mraheil, Mobarak Abu Mohamed, Walid Chakraborty, Trinad Ilinskaya, Olga
Copyright Year	2017
Abstract	Natural components, particularly those derived from medicinal plants, provide a promising source of new antimicrobial agents for the treatment of respiratory infections. In this work, we studied the antimicrobial potency of Thymus capitatus ethanolic extract against nine microorganisms isolated from clinical material obtained from patients admitted to hospitals in Egypt and Germany with infections of the respiratory tract (bacterial sinusitis, laryngitis, pharyngitis and bronchitis) using the disc diffusion assay and minimum inhibitory concentration (MIC) values. All isolates obtained from the Giessen University Clinic (Germany) exhibit susceptibility of different extent to the plant extract tested. The growth inhibition zone diameters for nine strains were in the range of 13–15.5 mm at a concentration of 5 mg/disc. The extract produced large inhibition zones of 14–17 mm diameters for seven microbial strains obtained in Egypt although it failed to inhibit the growth of isolates of Staphylococcus epidermidis and Enterococcus faecalis. In fact, most of the respiratory tract infections isolates from Egypt were generally more susceptible to the ethanolic extract of Thymus capitatus at lower MIC values than those obtained from Giessen University Clinic MIC values. The results of this study suggest that further delineation of bioactive phytomolecules of Thymus capitatus ethanolic extract will improve their potential application for the treatment of respiratory tract diseases.
Starting Page	644
Ending Page	647
Page Count	4
File Format	PDF
ISSN	21911630
Journal	BioNanoScience
Volume Number	7
Issue Number	4
e-ISSN	21911649
Language	English
Publisher	Springer US
Publisher Date	2017-10-15
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Antimicrobial activity Plant extract Thymus capitatus Respiratory tract infections Minimum inhibitory concentration Circuits and Systems Biological and Medical Physics, Biophysics Nanotechnology Biomaterials
Content Type	Text
Resource Type	Article
Subject	Bioengineering Biomedical Engineering

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