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| Content Provider | Springer Nature Link |
|---|---|
| Author | Ebrahiminezhad, Alireza Rasoul Amini, Sara Ghasemi, Younes |
| Copyright Year | 2011 |
| Abstract | l-Asparaginase is an anti-neoplastic drug used in lymphoblastic leukemia chemotherapy. Nowadays, this enzyme derived from bacterial sources, mostly l-asparaginase II from Escherichia coli and in lesser amount l-asparaginase of Erwinia sp. has medical utilization. The long-term usage of these agents leads to allergic reactions and new asparaginase with new immunological characteristics is required. Halophilic bacteria might contain l-asparaginase with novel immunological properties that can be used in hypersensitive patients. In this experiment, we have screened moderate Halophilic bacteria for l-asparaginase production ability and showed that Halophilic bacteria produce intra- and extracellular l-asparaginase. Bacillus sp. BCCS 034 was found to produce the highest l-asparaginase (1.64 IU/ml supernatant) extracellularly. |
| Starting Page | 307 |
| Ending Page | 311 |
| Page Count | 5 |
| File Format | |
| ISSN | 00468991 |
| Journal | Indian Journal of Microbiology |
| Volume Number | 51 |
| Issue Number | 3 |
| e-ISSN | 09737715 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2011-02-01 |
| Publisher Institution | Association of Microbiologists of India |
| Publisher Place | India |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | l-Asparaginase Halophile Bacteria 16S rRNA Medical Microbiology Microbiology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Microbiology |
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