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Indian Journal of Microbiology : Volume 51, Issue 2, June 2011

Indian Journal of Microbiology : Volume 51, Issue 1, January 2011

Indian Journal of Microbiology : Volume 50

Indian Journal of Microbiology : Volume 49

Indian Journal of Microbiology : Volume 48

Indian Journal of Microbiology : Volume 47

Virulence Factors and Anti Fungal Sensitivity Pattern of Candida Sp. Isolated from HIV and TB Patients

Content Provider	Springer Nature Link
Author	Ramesh, Nachimuthu Priyadharsini, Maruthupandian Sumathi, Chettipalayam Samiappan Balasubramanian, Velramar Hemapriya, Janarthanam kannan, Rajesh
Copyright Year	2011
Abstract	The study comprised of 60 Candida spp., 50 isolates from HIV and TB positive individuals (immunocompromised) and 10 isolates from non-HIV and -TB patients (immunocompetent). Among the 60 Candidal isolates, 83.3% were identified as C. albicans, 11.6% as C. glabrata and rest 5% as C. krusei. There is no study in production pattern of extracellular enzymes of Candida spp. isolated from HIV and TB patients in comparison with non-HIV and -TB patients in India. The comparison of phospholipase activities showed that there was a significant difference between the groups at (P = 0.001). The non-HIV and -TB groups of C. glabrata and C. krusei did not show detectable phospholipase activity when compared to the HIV and TB groups. The mean difference in the phospholipase activities of these two groups was significant (P = <0.001). Candida spp. of both the groups do not possess the ability to hydrolyze gelatin. All the strains possessed the ability to show alpha haemolysis. Even though it had shown alpha haemolysis, the significant difference in haemolytic activity was observed only in C. albicans (P = <0.001). None of the isolates from the two groups possessed the ability to hydrolyze gelatin. In the resistance profile of Candida spp., C. albicans of HIV and TB groups had shown resistance to fluconazole, Itraconazole, ketaconazole, nystatin but showed 100% sensitivity towards amphotericin-B. The isolates of C. krusei and C. glabrata showed no resistance to any of the drugs tested. In the case of, non-HIV and -TB patients the resistance pattern was low.
Starting Page	273
Ending Page	278
Page Count	6
File Format	PDF
ISSN	00468991
Journal	Indian Journal of Microbiology
Volume Number	51
Issue Number	3
e-ISSN	09737715
Language	English
Publisher	Springer-Verlag
Publisher Date	2011-04-09
Publisher Institution	Association of Microbiologists of India
Publisher Place	India
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Candida Protease Lipase Fluconazole HIV TB Medical Microbiology Microbiology
Content Type	Text
Resource Type	Article
Subject	Microbiology

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