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| Content Provider | Springer Nature Link |
|---|---|
| Author | Wang, Leyi Hayes, Jeff Byrum, Beverly Zhang, Yan |
| Copyright Year | 2016 |
| Abstract | Porcine epidemic diarrhea virus (PEDV) was first recognized in pigs in the United States (US) in May 2013. Since then, the virus has spread to over 30 states and caused significant economic losses in the US swine industry due to the high mortality in newborn piglets less than 2 weeks of age. A mild-variant strain OH851 of PEDV in the US was first reported in January 2014. Here, we report histological changes in the small intestines of five piglets infected with the variant strain OH851 of PEDV. The lesions observed were milder, compared to the US classical strain of PEDV. Our study, for the first time, reports the histological lesions caused by the variant PEDV OH851 strain from a field case. In addition, genomic characterization demonstrated that US variant PEDV is more closely related to European-like strains in the first 1170 nt of the 5′ spike gene but to US classical PEDV strains in the remaining genome, suggesting that the variant PEDV strain may derive from a recombinant event between the US classical and European-like PEDV strains. |
| Starting Page | 578 |
| Ending Page | 581 |
| Page Count | 4 |
| File Format | |
| ISSN | 09208569 |
| Journal | Virus Genes |
| Volume Number | 52 |
| Issue Number | 4 |
| e-ISSN | 1572994X |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2016-04-08 |
| Publisher Place | New York |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Porcine epidemic diarrhea virus PEDV Variant strain Histological lesion Genetic characterization Medical Microbiology Virology Plant Sciences |
| Content Type | Text |
| Resource Type | Article |
| Subject | Virology Genetics Medicine Molecular Biology |
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