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  1. Journal of Bioenergetics and Biomembranes
  2. Journal of Bioenergetics and Biomembranes : Volume 35
  3. Journal of Bioenergetics and Biomembranes : Volume 35, Issue 6, December 2003
  4. β Subunits of Voltage-Gated Calcium Channels
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Journal of Bioenergetics and Biomembranes : Volume 49
Journal of Bioenergetics and Biomembranes : Volume 48
Journal of Bioenergetics and Biomembranes : Volume 47
Journal of Bioenergetics and Biomembranes : Volume 46
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Journal of Bioenergetics and Biomembranes : Volume 44
Journal of Bioenergetics and Biomembranes : Volume 43
Journal of Bioenergetics and Biomembranes : Volume 42
Journal of Bioenergetics and Biomembranes : Volume 41
Journal of Bioenergetics and Biomembranes : Volume 40
Journal of Bioenergetics and Biomembranes : Volume 39
Journal of Bioenergetics and Biomembranes : Volume 38
Journal of Bioenergetics and Biomembranes : Volume 37
Journal of Bioenergetics and Biomembranes : Volume 36
Journal of Bioenergetics and Biomembranes : Volume 35
Journal of Bioenergetics and Biomembranes : Volume 35, Issue 6, December 2003
Calcium Channels: Unanswered Questions
Neurotransmitter Modulation of Neuronal Calcium Channels
Molecular Pharmacology of High Voltage-Activated Calcium Channels
Effects of Toxic Environmental Contaminants on Voltage-Gated Calcium Channel Function: From Past to Present
Low-Voltage-Activated (“T-Type”) Calcium Channels in Review
Modulation and Pharmacology of Low Voltage-Activated (“T-Type”) Calcium Channels
β Subunits of Voltage-Gated Calcium Channels
Targeting Mechanisms of High Voltage-Activated Ca$^{2+}$ Channels
Calcium Channel α$_{2}$δ Subunits: Differential Expression, Function, and Drug Binding
The Voltage-Gated Calcium Channel γ Subunits: A Review of the Literature
Nonchannel Functions of the Calcium Channel γ Subunit: Insight from Research on the Stargazer Mutant
In Vivo Analysis of Voltage-Dependent Calcium Channels
Voltage-Operated Calcium Channel Heterogeneity in Pancreatic β Cells: Physiopathological Implications
Ca$^{2+}$ Channels as Targets of Neurological Disease: Lambert–Eaton Syndrome and Other Ca$^{2+}$ Channelopathies
Journal of Bioenergetics and Biomembranes : Volume 35, Issue 5, October 2003
Journal of Bioenergetics and Biomembranes : Volume 35, Issue 4, August 2003
Journal of Bioenergetics and Biomembranes : Volume 35, Issue 3, June 2003
Journal of Bioenergetics and Biomembranes : Volume 35, Issue 2, April 2003
Journal of Bioenergetics and Biomembranes : Volume 35, Issue 1, February 2003
Journal of Bioenergetics and Biomembranes : Volume 34
Journal of Bioenergetics and Biomembranes : Volume 33
Journal of Bioenergetics and Biomembranes : Volume 32
Journal of Bioenergetics and Biomembranes : Volume 31
Journal of Bioenergetics and Biomembranes : Volume 30
Journal of Bioenergetics and Biomembranes : Volume 29

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β Subunits of Voltage-Gated Calcium Channels

Content Provider Springer Nature Link
Author Dolphin, Annette C.
Copyright Year 2003
Abstract Calcium channel β subunits have marked effects on the trafficking and on several of the biophysical properties of all high voltage activated calcium channels. In this article I shall review information on the different genes, on the structure of the β subunits, and on their differential expression and post-translational modification. Their role in trafficking and assembly of the calcium channel heteromultimer will be described, and I will then review their effects on voltage-dependent and kinetic properties, stressing the differences between palmitoylated β2a and the other β subunits. Evidence for effects on calcium channel pharmacology will also be examined. I shall discuss the hypothesis that β subunits can bind reversibly to calcium channels, and examine their role in the G protein modulation of calcium channels. Finally, I shall describe the consequences of knock-out of different β subunit genes, and describe evidence for the involvement of β subunits in disease.
Starting Page 599
Ending Page 620
Page Count 22
File Format PDF
ISSN 0145479X
Journal Journal of Bioenergetics and Biomembranes
Volume Number 35
Issue Number 6
e-ISSN 15736881
Language English
Publisher Kluwer Academic Publishers-Plenum Publishers
Publisher Date 2003-01-01
Publisher Place New York
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword Organic Chemistry Bioorganic Chemistry Biochemistry Animal Biochemistry Animal Anatomy / Morphology / Histology
Content Type Text
Resource Type Article
Subject Cell Biology Physiology
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