NDLI: K$^{+}$ and Ca$^{2+ }$modified Na-X zeolites as possible bile acids sequestrant

Content Provider	Springer Nature Link
Author	Linares, Carlos F. Valenzuela, Elymar Ocanto, Freddy Pérez, Víctor Valbuena, Oscar Goldwasser, Mireya R.
Copyright Year	2007
Abstract	Modified zeolite X, previously exchanged with K$^{+}$ and Ca$^{2+}$ cations were characterized by XRD, FT-IR, chemical analysis and BET techniques. Different masses of these solids were mixed with an ox bile solution at different reaction times. The supernatants obtained by centrifugations were submitted to bile acid and phospholipids quantitative determinations. The amount of bile acids adsorbed was 65, 28 and 77% and for phospholipids was 45, 67 and 98% for KX, NaX and CaX respectively. As expected, as the amount of mass used increases more bile acids and phospholipids are adsorbed due to a larger surface of the solid being available for adsorption. On the other hand, 120 min of reaction time were sufficient for the adsorption of both components. The solids, after incubations with bile solutions were treated with abundant distilled water and dried at room temperature. The FT-IR analysis of these solids did not detect any bile and on the zeolite surface with suggested that the bile acid adsorption on the exchanged zeolites is moderated by weak and non covalent interactions.
Starting Page	2023
Ending Page	2028
Page Count	6
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	19
Issue Number	5
e-ISSN	15734838
Language	English
Publisher	Springer US
Publisher Date	2007-10-24
Publisher Place	Boston
Access Restriction	Subscribed
Subject Keyword	Surfaces and Interfaces, Thin Films Ceramics, Glass, Composites, Natural Methods Metallic Materials Polymer Sciences Characterization and Evaluation of Materials Biomaterials
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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