NDLI: Ion release from magnesium materials in physiological solutions under different oxygen tensions

Content Provider	Springer Nature Link
Author	Feyerabend, Frank Drücker, Heiko Laipple, Daniel Vogt, Carla Stekker, Michael Hort, rbert Willumeit, Regine
Copyright Year	2011
Abstract	Although magnesium as degradable biomaterial already showed clinical proof of concepts, the design of new alloys requires predictive in vitro methods, which are still lacking. Incubation under cell culture conditions to obtain “physiological” corrosion may be a solution. The aim of this study was to analyse the influence of different solutions, addition of proteins and of oxygen availability on the corrosion of different magnesium materials (pure Mg, WE43, and E11) with different surface finishing. Oxygen content in solution, pH, osmolality and ion release were determined. Corrosion led to a reduction of oxygen in solution. The influence of oxygen on pH was enhanced by proteins, while osmolality was not influenced. Magnesium ion release was solution-dependent and enhanced in the initial phase by proteins with delayed release of alloying elements. The main corrosion product formed was magnesium carbonate. Therefore, cell culture conditions are proposed as first step toward physiological corrosion.
Starting Page	9
Ending Page	24
Page Count	16
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	23
Issue Number	1
e-ISSN	15734838
Language	English
Publisher	Springer US
Publisher Date	2011-12-04
Publisher Place	Boston
Access Restriction	Subscribed
Subject Keyword	Metallic Materials Ceramics, Glass, Composites, Natural Methods Polymer Sciences Characterization and Evaluation of Materials Biomaterials Surfaces and Interfaces, Thin Films
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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