NDLI: Changes in bone mineral density and microarchitecture in cosmonauts after a six-month space flight

Content Provider	Springer Nature Link
Author	Prostyakov, I. V. Morukov, B. V. Morukov, I. B.
Copyright Year	2012
Abstract	The effect of microgravity on the bone tissue of cosmonauts has been studied after a six-month space flight. The volumetric bone mineral density (VBMD) and the bone structural characteristics of distal segments in the radius and tibia have been studied by means of peripheral quantitative computed tomography (pQCT). The changes in VBMD were found to correlate with the position of the bone relative to the vector of gravity. In the radius, reversible hypermineralization, together with thickening of the compact bone were recorded. In the tibia, reversible osteopenia was characterized by significant losses in both compact and trabecular bones. Irrespective of the position relative to the vector of gravity, there was a trend towards microarchitectural deterioration, such as a decrease in the trabecula number and increase in the bone tissue heterogeneity. Postflight dynamics of structural parameters showed an integrative character with nonlinear time dependence.
Starting Page	727
Ending Page	731
Page Count	5
File Format	PDF
ISSN	03621197
Journal	Human Physiology
Volume Number	38
Issue Number	7
e-ISSN	16083164
Language	English
Publisher	SP MAIK Nauka/Interperiodica
Publisher Date	2012-12-15
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Life Sciences Human Physiology Biomedicine general
Content Type	Text
Resource Type	Article
Subject	Physiology Physiology (medical)

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